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Database: UniProt
Entry: D2HLW8_AILME
LinkDB: D2HLW8_AILME
Original site: D2HLW8_AILME 
ID   D2HLW8_AILME            Unreviewed;       989 AA.
AC   D2HLW8;
DT   09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT   09-FEB-2010, sequence version 1.
DT   26-NOV-2014, entry version 30.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAMEP00000008208};
DE   Flags: Fragment;
GN   Name=EPB41L2 {ECO:0000313|Ensembl:ENSAMEP00000008208};
GN   ORFNames=PANDA_012520 {ECO:0000313|EMBL:EFB30246.1};
OS   Ailuropoda melanoleuca (Giant panda).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae;
OC   Ailuropoda.
OX   NCBI_TaxID=9646;
RN   [1] {ECO:0000313|EMBL:EFB30246.1, ECO:0000313|Ensembl:ENSAMEP00000008208}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=20010809; DOI=10.1038/nature08696;
RA   Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q.,
RA   Li B., Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H.,
RA   Jian M., Li J., Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z.,
RA   Ryder O.A., Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X.,
RA   Guo X., Wang B., Hou R., Shen F., Mu B., Ni P., Lin R., Qian W.,
RA   Wang G., Yu C., Nie W., Wang J., Wu Z., Liang H., Min J., Wu Q.,
RA   Cheng S., Ruan J., Wang M., Shi Z., Wen M., Liu B., Ren X., Zheng H.,
RA   Dong D., Cook K., Shan G., Zhang H., Kosiol C., Xie X., Lu Z.,
RA   Zheng H., Li Y., Steiner C.C., Lam T.T., Lin S., Zhang Q., Li G.,
RA   Tian J., Gong T., Liu H., Zhang D., Fang L., Ye C., Zhang J., Hu W.,
RA   Xu A., Ren Y., Zhang G., Bruford M.W., Li Q., Ma L., Guo Y., An N.,
RA   Hu Y., Zheng Y., Shi Y., Li Z., Liu Q., Chen Y., Zhao J., Qu N.,
RA   Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X., Vinar T., Wang Y.,
RA   Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y., Wang X.,
RA   Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA   Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H.,
RA   Wang J., Wang J.;
RT   "The sequence and de novo assembly of the giant panda genome.";
RL   Nature 463:311-317(2010).
RN   [2] {ECO:0000313|Ensembl:ENSAMEP00000008208}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
CC   -!- SIMILARITY: Contains FERM domain. {ECO:0000256|SAAS:SAAS00130622}.
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DR   EMBL; ACTA01194334; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; GL193025; EFB30246.1; -; Genomic_DNA.
DR   Ensembl; ENSAMET00000008549; ENSAMEP00000008208; ENSAMEG00000007667.
DR   GeneTree; ENSGT00760000118823; -.
DR   HOGENOM; HOG000228841; -.
DR   OMA; VGEYQPH; -.
DR   TreeFam; TF351626; -.
DR   GO; GO:0008180; C:COP9 signalosome; IEA:Ensembl.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR   GO; GO:0070062; C:extracellular vesicular exosome; IEA:Ensembl.
DR   GO; GO:0019898; C:extrinsic component of membrane; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:InterPro.
DR   Gene3D; 1.20.80.10; -; 1.
DR   Gene3D; 2.30.29.30; -; 1.
DR   InterPro; IPR008379; Band_4.1_C.
DR   InterPro; IPR019749; Band_41_domain.
DR   InterPro; IPR019750; Band_41_fam.
DR   InterPro; IPR021187; Band_41_protein.
DR   InterPro; IPR000798; Ez/rad/moesin_like.
DR   InterPro; IPR014847; FERM-adjacent.
DR   InterPro; IPR014352; FERM/acyl-CoA-bd_prot_3-hlx.
DR   InterPro; IPR019748; FERM_central.
DR   InterPro; IPR019747; FERM_CS.
DR   InterPro; IPR000299; FERM_domain.
DR   InterPro; IPR018979; FERM_N.
DR   InterPro; IPR018980; FERM_PH-like_C.
DR   InterPro; IPR011993; PH_like_dom.
DR   InterPro; IPR007477; SAB_dom.
DR   InterPro; IPR029071; Ubiquitin-rel_dom.
DR   Pfam; PF05902; 4_1_CTD; 1.
DR   Pfam; PF08736; FA; 1.
DR   Pfam; PF09380; FERM_C; 1.
DR   Pfam; PF00373; FERM_M; 1.
DR   Pfam; PF09379; FERM_N; 1.
DR   Pfam; PF04382; SAB; 1.
DR   PIRSF; PIRSF002304; Membrane_skeletal_4_1; 1.
DR   PRINTS; PR00935; BAND41.
DR   PRINTS; PR00661; ERMFAMILY.
DR   SMART; SM00295; B41; 1.
DR   SUPFAM; SSF47031; SSF47031; 1.
DR   SUPFAM; SSF54236; SSF54236; 1.
DR   PROSITE; PS00660; FERM_1; 1.
DR   PROSITE; PS00661; FERM_2; 1.
DR   PROSITE; PS50057; FERM_3; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008912};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008912}.
FT   NON_TER     989    989       {ECO:0000313|EMBL:EFB30246.1}.
SQ   SEQUENCE   989 AA;  110379 MW;  2B4DA17ADDFC6DAA CRC64;
     MTTEVGSASE VKKESEPLGA DATKEKPKEV AENQQNQSSD PEEEKGSQSS PTAESQSSPR
     RQKRDKDPSE SRGISRFIPP WLKKQKSYTL VAAKDGGDKK EPAQAVVEEV LDKEESLPEG
     DGQAKGDAGE TALRKQQEMK VDVKEEKPSV SRPEAQPAEE VGKEREEKVK EMQEDKSEEA
     AKRETKEVQT NELKAERALQ KAGKKTKAVQ CKVILLDGTE YSCDLEKRAK GQVLFDKVCE
     HLNLLEKDYF GLLFQESPEQ KNWLDPAKEI KRQLRNLPWL FTFNVKFYPP DPSQLTEDLT
     RYFLCLQLRQ DIASGRLPCS FVTHALLGSY TLQAELGDYD PEEHGSSDLS DFQFAPTQTK
     ELEEKVAELH KTHRGLSPAQ ADSQFLENAK RLSMYGVDLH HAKDSEGVDI KLGVCANGLL
     IYKDRLRINR FAWPKILKIS YKRSNFYIKV RPAELEQFES TIGFKLPNHR AAKRLWKVCV
     EHHTFYRLVS PEQPPKAKFL TLGSKFRYSG RTQAQTRQAS TLIDRPAPHF ERTSSKRVSR
     SLDGAPVGVV DESLRKDFPG PAGEISAYGP EVVSTAMVQD GDGRRDLRSP AKAPHVQFIE
     GKKNSLRVEG DNIYVRHSNL MLEDLDKAQE DILRHQASIS ELKRNFMEST PEPRPNEWEK
     RRITPLSLQT QGSSHETLNV VEEKKQAEVG KDERVITEEM NGKELSPGSG PGEMRKAEPL
     TQKDSTSLSS ESSSSSESEE EDAGEYRPHH RGTEGTIREE QEEEEAGRAA KVVEREHPVP
     GASPGRQAGA SVSTVETEIQ ENVVAPKIPA EKSVNEGAIK QDMSEETEDE QHKVNGEVSH
     VDIDVLPQII CCSEPPVVKT EMVTISDASQ RTEISTKEVP IVQTETKTIT YESPQIDGGA
     GGDSGTLLTA QTITSESVST TTTTHITKTV KGGISETRIE KRIVITGDAD IDHDQALAQA
     IREAREQHPD MSVTRVVVHK ETELEEGEE
//
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