ID D2HS77_AILME Unreviewed; 716 AA.
AC D2HS77;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=B30.2/SPRY domain-containing protein {ECO:0000259|PROSITE:PS50188};
DE Flags: Fragment;
GN ORFNames=PANDA_014917 {ECO:0000313|EMBL:EFB28154.1};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|EMBL:EFB28154.1};
RN [1] {ECO:0000313|EMBL:EFB28154.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; GL193267; EFB28154.1; -; Genomic_DNA.
DR RefSeq; XP_002925424.2; XM_002925378.3.
DR AlphaFoldDB; D2HS77; -.
DR GeneID; 100466358; -.
DR KEGG; aml:100466358; -.
DR CTD; 221092; -.
DR HOGENOM; CLU_012140_1_0_1; -.
DR InParanoid; D2HS77; -.
DR OrthoDB; 5402316at2759; -.
DR CDD; cd12884; SPRY_hnRNP; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR035778; SPRY_hnRNP_U.
DR PANTHER; PTHR12381; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER; 1.
DR PANTHER; PTHR12381:SF66; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U-LIKE PROTEIN 2; 1.
DR Pfam; PF13671; AAA_33; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
PE 4: Predicted;
FT DOMAIN 195..388
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 1..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 596..635
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..66
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..203
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 596..610
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EFB28154.1"
FT NON_TER 716
FT /evidence="ECO:0000313|EMBL:EFB28154.1"
SQ SEQUENCE 716 AA; 81353 MW; DB584F84568F5752 CRC64;
DLAQRLQEAL DAEMLEDEAG GGGGGGAEPR PVAASGGGPG GDEEDDEEEE EEDEEALLED
EDEEPPPAQA SGQAAQPPPE PPEAAAMEAA AEPDASEKPA EEATAGSGGV NGGEEQGTGK
GEEDEPEERS GDETPGSEAP GDKAAEEQGD DQDSEKSKPA GSDGERRGVK RQRDEKDEHG
RAYYEFREEA YHSRSKSPPP PEEEAKDEAE DQTLVNLDTY TSDLHFQVSK DRYGGQPLFS
EKFPTLWSGA RSTYGVTKGK VCFEAKVTQN LPMKEGCTEV SLLRVGWSVD FSHPQLGEDE
FSYGFDGRGL KAENGQFEEF GQTFGENDVI GCFANFETEE VELSFSKNGE DLGVAFRINK
ESLAERALLP HVLCKNCVVE LNFGQKEEPF FPPPEEFVFI HAVPVEERVR TAVPPKTIEE
CEVILMVGLP GSGKTQWALK YAKENPEKRY NVLGAETVLN QMRMKGLEEP EMDPKSRDLL
VQQASQCLSK LVQIASRTKR NFILDQCNVY NSGQRRKLLL FKTFSRKVVV VVPNEEDWKK
RLELRKEVEG DDVPESIMLE MKANFSLPEK CDYMDEVTYG ELEKEEAQPI VTKYKEEARK
LLPPSEKRTN RRNNRNKRNR QNRSRGQGYV GGQRRGYDNR AYGQQYWGQS GNRGGYRNFY
DRYRGDYDRF YGRDYEYNRY RDYYRQYNRD WQNYYYHHPQ DRDRYYRNYY GYQGYR
//
