ID D2JM58_FUSCE Unreviewed; 376 AA.
AC D2JM58;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Cytochrome P450 monooxygenase {ECO:0000313|EMBL:ACZ56381.1};
DE Flags: Fragment;
GN Name=TRI11 {ECO:0000313|EMBL:ACZ56381.1};
OS Fusarium cerealis (Fusarium crookwellense).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=56641 {ECO:0000313|EMBL:ACZ56381.1};
RN [1] {ECO:0000313|EMBL:ACZ56381.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FRC R-09624 {ECO:0000313|EMBL:ACZ56381.1};
RX PubMed=19843228; DOI=10.1111/j.1365-2958.2009.06927.x;
RA Proctor R.H., McCormick S.P., Alexander N.J., Desjardins A.E.;
RT "Evidence that a secondary metabolic biosynthetic gene cluster has grown by
RT gene relocation during evolution of the filamentous fungus Fusarium.";
RL Mol. Microbiol. 74:1128-1142(2009).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR EMBL; GQ915559; ACZ56381.1; -; Genomic_DNA.
DR AlphaFoldDB; D2JM58; -.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd11058; CYP60B-like; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24305:SF29; BENZOATE-PARA-HYDROXYLASE; 1.
DR PANTHER; PTHR24305; CYTOCHROME P450; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|RuleBase:RU000461};
KW Iron {ECO:0000256|RuleBase:RU000461};
KW Metal-binding {ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|RuleBase:RU000461, ECO:0000313|EMBL:ACZ56381.1};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461}.
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACZ56381.1"
SQ SEQUENCE 376 AA; 42016 MW; 715C125033737B8D CRC64;
HMKYGPVVRI GPNMLSFNHP DAMKDVRGHR KSGEAEHGKD PIIVLSNGDN IVGSDRENHT
RFRRALAYGF SAQAMLEQEP TFKAYVNQLF QRLHEESSNG TKTVDISKWY TFTTFDMIGD
LAFGESFGCL DNSTYHPWVA LAFESLKSLA FMAEMGRYPR IAPYIGFLLP RGLLNKFAEN
KELASMKVRK RLDTETDRPD FVGKITQGLK AKGSSMEFNE LASNASVLIV AGSETTATLL
SAAVYFLCSN PRTLELLAEE VRSTYTQADA IDLVSTQGLR YMQAVLDEAL RMYPPVAGGG
SPRKIAKGGS FVAGYFVPEN TLVENDMWAM HYDPKYFTQP HDFIPERWLG DARFSSDRLD
AVKPFSIGPR NCIGMK
//
