ID D2K2N2_PLAVI Unreviewed; 339 AA.
AC D2K2N2;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Merozoite surface protein 1 {ECO:0000256|ARBA:ARBA00022062};
DE AltName: Full=Merozoite surface antigen {ECO:0000256|ARBA:ARBA00031689};
DE AltName: Full=PMMSA {ECO:0000256|ARBA:ARBA00032276};
DE Flags: Fragment;
GN Name=MSP-1 {ECO:0000313|EMBL:ACZ67758.1};
OS Plasmodium vivax (malaria parasite P. vivax).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=5855 {ECO:0000313|EMBL:ACZ67758.1};
RN [1] {ECO:0000313|EMBL:ACZ67758.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CPV4526 {ECO:0000313|EMBL:ACZ67758.1};
RX PubMed=20933611; DOI=10.1016/j.meegid.2010.09.007;
RA Dias S., Longacre S., Escalante A.A., Udagama-Randeniya P.V.;
RT "Genetic diversity and recombination at the C-terminal fragment of the
RT merozoite surface protein-1 of Plasmodium vivax (PvMSP-1) in Sri Lanka.";
RL Infect. Genet. Evol. 11:145-156(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004609};
CC Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}. Membrane
CC {ECO:0000256|ARBA:ARBA00004589}; Lipid-anchor, GPI-anchor
CC {ECO:0000256|ARBA:ARBA00004589}.
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DR EMBL; GU175250; ACZ67758.1; -; Genomic_DNA.
DR AlphaFoldDB; D2K2N2; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR010901; MSP1_C.
DR InterPro; IPR024730; MSP1_EGF_1.
DR Pfam; PF12946; EGF_MSP1_1; 1.
DR Pfam; PF07462; MSP1_C; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Merozoite {ECO:0000313|EMBL:ACZ67758.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 1..193
FT /note="Merozoite surface 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07462"
FT DOMAIN 263..299
FT /note="Merozoite surface protein EGF"
FT /evidence="ECO:0000259|Pfam:PF12946"
FT COILED 106..202
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 339
FT /evidence="ECO:0000313|EMBL:ACZ67758.1"
SQ SEQUENCE 339 AA; 38861 MW; 7A775AF97B8FE6FA CRC64;
MYKTIKKQLE NHVNAFNTNI TDMLDSRLKK RNYFLEVLNS DLNPFKYSSS GEYIIKDPYK
LLDLEKKKKL LGSYKYIGAS IDKDLATAND GVAYYNKMEE LYKTHLTAVN AQIKKVEDDI
NTQNEELKKI ENEANKTAEK AKFTAKKAEL EKYLPFLNSL QKEYESLVSK VNTYTDNLKK
VINNCQLEKK EAEITVKKLQ DYNKMDEKLE EYKKSEKKNE VKSSGLLEKL MKSKLIKENE
SKEILSQLLN VQTQLLTMSS EHTCIDTNVP DNAACYRYLD GTEEWRCLLT FKEEGGKCVP
ASNVTCKDNN GGCAPEAECK MTDSNKIVCK CTKEGSEPL
//
