ID   D2KNP2_ANAPH            Unreviewed;      1206 AA.
AC   D2KNP2;
DT   09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT   09-FEB-2010, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=AnkA {ECO:0000313|EMBL:ADA72276.1};
GN   Name=ankA {ECO:0000313|EMBL:ADA72276.1};
OS   Anaplasma phagocytophilum (Ehrlichia phagocytophila).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC   Anaplasmataceae; Anaplasma; phagocytophilum group.
OX   NCBI_TaxID=948 {ECO:0000313|EMBL:ADA72276.1};
RN   [1] {ECO:0000313|EMBL:ADA72276.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Dog_30 {ECO:0000313|EMBL:ADA72276.1};
RX   PubMed=21177886; DOI=10.1128/JCM.02051-10;
RA   Scharf W., Schauer S., Freyburger F., Petrovec M., Schaarschmidt-Kiener D.,
RA   Liebisch G., Runge M., Ganter M., Kehl A., Dumler J.S., Garcia-Perez A.L.,
RA   Jensen J., Fingerle V., Meli M.L., Ensser A., Stuen S., von Loewenich F.D.;
RT   "Distinct host species correlate with Anaplasma phagocytophilum ankA gene
RT   clusters.";
RL   J. Clin. Microbiol. 49:790-796(2011).
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DR   EMBL; GU236838; ADA72276.1; -; Genomic_DNA.
DR   AlphaFoldDB; D2KNP2; -.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 5.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   PANTHER; PTHR24178:SF9; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR24178; MOLTING PROTEIN MLT-4; 1.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF12796; Ank_2; 2.
DR   PRINTS; PR01415; ANKYRIN.
DR   SMART; SM00248; ANK; 15.
DR   SUPFAM; SSF48403; Ankyrin repeat; 2.
DR   PROSITE; PS50297; ANK_REP_REGION; 4.
DR   PROSITE; PS50088; ANK_REPEAT; 5.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023}.
FT   REPEAT          44..76
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          216..248
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          672..712
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          713..745
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          827..859
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REGION          986..1145
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1158..1206
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1000..1017
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1046..1061
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1082..1114
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1206 AA;  127878 MW;  22B47847BFDD28ED CRC64;
     MLTEEEKKKS ACALQAIITG DYDSFQASIQ GISSEGLNTP VDKEGRTLLH YAASSRNGNF
     YGILVERGCV TNLKDAYGFT PEQARKKAGH ARTQWYGADV NDPGVSRQLM TQAVQQSAKG
     NMYGALAILD LVRNDDANIQ INEKGHGVLH LACIEGSDPS FTSSLMLKGC SLNIKDVDGN
     TPLHTAVTSV GRNALGNLDV LCDKALIADV NAKGPGGNTP LHIATERMDH QKVDHLLSRL
     GDISIANDAG ETVCHIVAKQ WPRRDVLAYI DKMQEAVSSN IEGNRECAEA LIFPDKKGMS
     AVQYAIRRHI PEAEQIFENA INIADKVYGS ASPEVKSLFT CPNPEDASTL VHFVSSNGTP
     NFDPLAKRVL EEAYHRYGGE PFTNLDIAGN APIHAAAQRS TVAVFEQLAR YTPESVVNQL
     APNGKAPIHM IVEDEPSHKG VSVKLQMLIE NVRNIPSINV PSPVTGETPV VAAYKGGNTE
     DVKTMLRCNS MDVDAQSHDG KTIIHHAAKD GNLEILQQAL GRKSSYSKFP VKDGVPTPGV
     YAIREASDGK KVSLPALDML MSYEPHPQHV AVEAVRKGAA DVLRHFIATE VISVNEEITT
     PEGKKTTLTA EALTNGQYAA VKTLIKNRAD VNASPEPAIS AGIQGGCFQG GKAIKHLKRV
     VEAGAHINTP PGSMSPLAAA VQSANEASNP KAANRIVNFL LQRGADLSST DHIGTPALHL
     ATAAGNHKTA KLLLDKGAPA TQRDAYGKTA LHIAAANGDG KLYKLIAKKC PDSCRPLSSH
     MGDTALHEAL YSDKVTEKCF LKMLKESRKH LSDSSFKDLL NTPQEANGDT LLHLAASRGF
     GKACKVLLKA GASVSVVNVE GKTPVDVADP SLKARPWLFG KSVVTMMAER VQVPEGGFPP
     YLPPESPTPS LGSISSFDSV TVLSSLGSGL DTAGPEESIY EEIKDTAKGA TGVESIYATV
     GAEGPRTPEG EDLYATVGAA ITSEAQASDA ASSKGERPES IYADPFDIVK PRQERPESIY
     ADPFAAERTS SSGLTTFGPK EEPIYATVKK GPKKSDTSQK EGTASEKVSP TITVMKKKVK
     PQVPTRTSSL PTKEGIGSDK DLSSGTSSSF AAELQAQRGK LRPVKGGAPD STKDKTATSV
     FSSEEFKKEL TKAAEGLQGA VEAQKGDGGA AKAKQDLGME SGAPGSQPEA PQSEGPKSVK
     GGGRGR
//