ID D2KQB2_PATMI Unreviewed; 560 AA.
AC D2KQB2;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=ErgS ETS transcription factor {ECO:0000313|EMBL:ADA79645.1};
OS Patiria miniata (Bat star) (Asterina miniata).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Asterozoa; Asteroidea;
OC Valvatacea; Valvatida; Asterinidae; Patiria.
OX NCBI_TaxID=46514 {ECO:0000313|EMBL:ADA79645.1};
RN [1] {ECO:0000313|EMBL:ADA79645.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=19941847; DOI=10.1016/j.ydbio.2009.11.020;
RA McCauley B.S., Weideman E.P., Hinman V.F.;
RT "A conserved gene regulatory network subcircuit drives different
RT developmental fates in the vegetal pole of highly divergent echinoderm
RT embryos.";
RL Dev. Biol. 340:200-208(2010).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
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DR EMBL; GU251974; ADA79645.1; -; mRNA.
DR AlphaFoldDB; D2KQB2; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR003118; Pointed_dom.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849:SF304; DNA-BINDING PROTEIN D-ETS-3-RELATED; 1.
DR PANTHER; PTHR11849; ETS; 1.
DR Pfam; PF00178; Ets; 1.
DR Pfam; PF02198; SAM_PNT; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SMART; SM00251; SAM_PNT; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR PROSITE; PS51433; PNT; 1.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004019}.
FT DOMAIN 148..233
FT /note="PNT"
FT /evidence="ECO:0000259|PROSITE:PS51433"
FT DOMAIN 391..471
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 1..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 109..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 239..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 346..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..76
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 560 AA; 62272 MW; DEAF30D57FA53671 CRC64;
MFESTYQHHH QEVPKTSSVS SAVSPHHHSS ALQSAVQKPK LSPQSSPVVD HGNTLPSPQQ
QQQQQQQQQQ QWAQCRQQEI IRMKQEPDHG SHGHEAGSLG GRVVEAESPL DCSVTKRQPH
GAMTEATQAA PPYPCPPYPG SESDRARSPP PNVTTNEKRV IVPADPNMWT IDHVQQWVQW
AVREYSLQDV LVSRFGIDGK QLCKMTREDF TRLTSSYNAD VLLSHLNFLK QAPLPNLTSD
DVDKALQPSP RAPPSPQATN IGTAQPITEK KYTCNATNYY PDQMQKASAS AFPYPVSSHV
DTNSRMQRTE PSCAESLVRG RQNSWASSVP VSSSKGFTQT TTSIPKAGIE SSTQIRPDPY
QVFGPTSRTL ANPENPASSL GGNVWNRSGQ IQLWQFLLEL LSDSSNANCI TWEGTNGEFK
MTDPDEVARR WGERKSKPNM NYDKLSRALR YYYDKNIMTK VHGKRYAYKF DFAGLAQAMQ
PVQADPSVYR YQSDLSYLAQ GYHHPSKINF VGTPIPSTNA GLFSSHGSYW SSPSAANIYP
SSHVTHPHSH VSPHIGTYYG
//
