ID D2PD82_SULID Unreviewed; 352 AA.
AC D2PD82;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Peptidase M24 {ECO:0000313|EMBL:ADB87652.1};
GN OrderedLocusNames=LD85_1997 {ECO:0000313|EMBL:ADB87652.1};
OS Sulfolobus islandicus (strain L.D.8.5 / Lassen #2).
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Sulfolobus.
OX NCBI_TaxID=425944 {ECO:0000313|EMBL:ADB87652.1, ECO:0000313|Proteomes:UP000001404};
RN [1] {ECO:0000313|Proteomes:UP000001404}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L.D.8.5 / Lassen #2 {ECO:0000313|Proteomes:UP000001404};
RX PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT "Biogeography of the Sulfolobus islandicus pan-genome.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
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DR EMBL; CP001731; ADB87652.1; -; Genomic_DNA.
DR RefSeq; WP_012713958.1; NC_013769.1.
DR AlphaFoldDB; D2PD82; -.
DR GeneID; 8761834; -.
DR KEGG; sii:LD85_1997; -.
DR HOGENOM; CLU_017266_4_0_2; -.
DR Proteomes; UP000001404; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01092; APP-like; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 1.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR001714; Pept_M24_MAP.
DR InterPro; IPR001131; Peptidase_M24B_aminopep-P_CS.
DR PANTHER; PTHR46112; AMINOPEPTIDASE; 1.
DR PANTHER; PTHR46112:SF9; XAA-PRO AMINOPEPTIDASE; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR PRINTS; PR00599; MAPEPTIDASE.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
DR PROSITE; PS00491; PROLINE_PEPTIDASE; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 3..130
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 137..339
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
SQ SEQUENCE 352 AA; 39701 MW; D2ED1FCB8A3844D2 CRC64;
MNRLRKLKAI LEDKKDSCAI ILGSPNLFYF LEYSGAGALV YCDSRFTLLV PALEMYRAEN
VKDVDIVIYY PSKILENVIE GNIFKAIEKI INKNSIMVDV NWVDASTYRA LSEKYRVMDF
SNEITRLREV KDDDEIERIR KAGEITAVAM KIGMEKLSEG TSNEKQVAGI IDMTMKSMGA
EDYAFPSIVA FGENSAYPHH IPTDRVLRNN DIVLFDIGAK YNGYCFDSTR TFVFKNSEAK
KVYEIVLEAQ MEAIDIVRDG IVASEVDVIA RRVIEKAGYG KYFIHSTGHG VGVEIHESPA
ISMNSKQILK ENMIITVEPG IYLKGRFGIR IEDTLIVTKG KPIVLETAYK LL
//
