ID D2PH22_SULID Unreviewed; 339 AA.
AC D2PH22;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=TrkA-N domain protein {ECO:0000313|EMBL:ADB88387.1};
GN OrderedLocusNames=LD85_2781 {ECO:0000313|EMBL:ADB88387.1};
OS Sulfolobus islandicus (strain L.D.8.5 / Lassen #2).
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Sulfolobus.
OX NCBI_TaxID=425944 {ECO:0000313|EMBL:ADB88387.1, ECO:0000313|Proteomes:UP000001404};
RN [1] {ECO:0000313|Proteomes:UP000001404}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L.D.8.5 / Lassen #2 {ECO:0000313|Proteomes:UP000001404};
RX PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT "Biogeography of the Sulfolobus islandicus pan-genome.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001731; ADB88387.1; -; Genomic_DNA.
DR RefSeq; WP_012714464.1; NC_013769.1.
DR AlphaFoldDB; D2PH22; -.
DR GeneID; 8762620; -.
DR KEGG; sii:LD85_2781; -.
DR HOGENOM; CLU_822869_0_0_2; -.
DR Proteomes; UP000001404; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR PANTHER; PTHR43833:SF5; TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKA; 1.
DR Pfam; PF02080; TrkA_C; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS51202; RCK_C; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 129..249
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 283..337
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 339 AA; 37598 MW; BF46490545A2F37C CRC64;
MDKGKIWNRI VIPILENLVA PYSVFKRIYI QIMLLGVAVL INAIVFVNYQ HLDWISAIYA
GVNVVTTVGL YSPNIYQMTS TEKIILTLTI ILAVGLYTSI IQSIVATLIS RVTWNDAKAR
WRGRHMKGHT ILIGNGTEIL SAVRRLNRLG VDYIVLTSSK DIANNNRGDA VILGDPKDDN
NLISAGVNYA KNAIVIMEND MEALLITLKL QKLNPPLKVI VAIRDYSLTD LFKTAGADLV
IPREDIIGRI AASAALSTNI AGLIFPERTG DMIIGIFEVK KAKKISDLPS EVVPLAIIRN
NKIDPYFNKD TELKPRDQLI ILGSPSTFQK VRELLELPD
//
