ID   D2PHA2_SULID            Unreviewed;       325 AA.
AC   D2PHA2;
DT   02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   02-MAR-2010, sequence version 1.
DT   27-MAR-2024, entry version 59.
DE   SubName: Full=FAD-dependent pyridine nucleotide-disulphide oxidoreductase {ECO:0000313|EMBL:ADB88467.1};
GN   OrderedLocusNames=LD85_2868 {ECO:0000313|EMBL:ADB88467.1};
OS   Sulfolobus islandicus (strain L.D.8.5 / Lassen #2).
OC   Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=425944 {ECO:0000313|EMBL:ADB88467.1, ECO:0000313|Proteomes:UP000001404};
RN   [1] {ECO:0000313|Proteomes:UP000001404}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L.D.8.5 / Lassen #2 {ECO:0000313|Proteomes:UP000001404};
RX   PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA   Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT   "Biogeography of the Sulfolobus islandicus pan-genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
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DR   EMBL; CP001731; ADB88467.1; -; Genomic_DNA.
DR   RefSeq; WP_012953326.1; NC_013769.1.
DR   AlphaFoldDB; D2PHA2; -.
DR   GeneID; 8762705; -.
DR   KEGG; sii:LD85_2868; -.
DR   HOGENOM; CLU_031864_5_3_2; -.
DR   Proteomes; UP000001404; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   PANTHER; PTHR48105:SF14; THIOREDOXIN REDUCTASE (TRXB-2); 1.
DR   PANTHER; PTHR48105; THIOREDOXIN REDUCTASE 1-RELATED-RELATED; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00469; PNDRDTASEII.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          6..290
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
SQ   SEQUENCE   325 AA;  35150 MW;  1B22BD59BB321C1E CRC64;
     MPLKTFDTII VGAGIAGLSA AVYSSRQKLS TLVLSKDLGG QLTLTDLIEN YPGIESTGGL
     SLAQKIEKQA KKFGAEFIYG EEVKEIAQES DVFIIKGIKG EYAGRAIILA FGKTPREINV
     PGEQEFKGKG VSYCAICDAA FFKGKPAAVV GEGEPGIEAI ELLSNYANPA YYITSSSYLA
     GEEEIVKNVL NKPNVKIFTS SKVLEIRGNS KVEEIMIKKG DEIISLRVDG VIIEMGYVLK
     TEFLKGFVEL NEKGEIVVDE LGRTSREGVF AAGDVTQTPY KQAVVAAAEG VKAALSAYNY
     IRSKKGLPPV NVDWKAEKKK VSFRL
//