ID D2PZH7_KRIFD Unreviewed; 375 AA.
AC D2PZH7;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Peptidase S1 and S6 chymotrypsin/Hap {ECO:0000313|EMBL:ADB33786.1};
GN OrderedLocusNames=Kfla_4769 {ECO:0000313|EMBL:ADB33786.1};
OS Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399).
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Kribbellaceae; Kribbella.
OX NCBI_TaxID=479435 {ECO:0000313|EMBL:ADB33786.1, ECO:0000313|Proteomes:UP000007967};
RN [1] {ECO:0000313|Proteomes:UP000007967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17836 / JCM 10339 / NBRC 14399
RC {ECO:0000313|Proteomes:UP000007967};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M.,
RA Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA Pukall R., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Kribbella flavida DSM 17836.";
RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADB33786.1, ECO:0000313|Proteomes:UP000007967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17836 / JCM 10339 / NBRC 14399
RC {ECO:0000313|Proteomes:UP000007967};
RX PubMed=21304701;
RA Pukall R., Lapidus A., Glavina Del Rio T., Copeland A., Tice H.,
RA Cheng J.-F., Lucas S., Chen F., Nolan M., LaButti K., Pati A., Ivanova N.,
RA Mavrommatis K., Mikhailova N., Pitluck S., Bruce D., Goodwin L., Land M.,
RA Hauser L., Chang Y.-J., Jeffries C.D., Chen A., Palaniappan K., Chain P.,
RA Rohde M., Goeker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.-P., Brettin T.;
RT "Complete genome sequence of Kribbella flavida type strain (IFO 14399).";
RL Stand. Genomic Sci. 2:186-193(2010).
CC -!- SIMILARITY: Belongs to the peptidase S1 family.
CC {ECO:0000256|ARBA:ARBA00007664}.
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DR EMBL; CP001736; ADB33786.1; -; Genomic_DNA.
DR RefSeq; WP_012922340.1; NC_013729.1.
DR AlphaFoldDB; D2PZH7; -.
DR STRING; 479435.Kfla_4769; -.
DR KEGG; kfl:Kfla_4769; -.
DR eggNOG; COG3064; Bacteria.
DR HOGENOM; CLU_030648_2_0_11; -.
DR OrthoDB; 3744945at2; -.
DR Proteomes; UP000007967; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd21112; alphaLP-like; 1.
DR Gene3D; 3.30.300.50; -; 2.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR004236; Pept_S1_alpha_lytic.
DR InterPro; IPR001316; Pept_S1A_streptogrisin.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR035070; Streptogrisin_prodomain.
DR Pfam; PF02983; Pro_Al_protease; 1.
DR PIRSF; PIRSF001134; Streptogrisin; 1.
DR PRINTS; PR00861; ALYTICPTASE.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR001134-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000007967};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..375
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003033442"
FT DOMAIN 113..169
FT /note="Peptidase S1A alpha-lytic prodomain"
FT /evidence="ECO:0000259|Pfam:PF02983"
FT ACT_SITE 218
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR001134-1"
FT ACT_SITE 246
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR001134-1"
FT ACT_SITE 329
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR001134-1"
FT DISULFID 203..219
FT /evidence="ECO:0000256|PIRSR:PIRSR001134-2"
FT DISULFID 286..296
FT /evidence="ECO:0000256|PIRSR:PIRSR001134-2"
FT DISULFID 323..350
FT /evidence="ECO:0000256|PIRSR:PIRSR001134-2"
SQ SEQUENCE 375 AA; 38304 MW; F87D0AD3F5703529 CRC64;
MKILVSTALV ASLLAVPAQA MAASPEQPLA VPRQTAALQK DLGLTEQQVK ELLRAEAAAT
KLVPAAQRAA GTAFGGTWYD AARQKLVVGV TSPAAADAVR ATGAEASVVP VTAAVLDRRK
AAVDKLAGTN VPAAVSGWSA DPRTGTVVVN VQAGKRSAAV DAFVDKVAKA GAVSVREVAA
QAPRTFAAGT VGGDPYYTGN VRCSIGFSVH GGFVTAGHCS GAGARTRGWD GSAQGVFRGS
SFPGNDYAWV QVDSGWWTVP VVLGWGQVSD QLVRGSWEAP VGTSVCRSGS TTHWHCGHIR
AKNETVNYGN GQLFYGATKT SVCAEGGDSG GSFITGDQAQ GVTSGGWGNC SSGGETWFQP
VNEILGAYGL TLHTA
//
