ID D2Q6I6_BIFDB Unreviewed; 339 AA.
AC D2Q6I6;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=LacI-type transcriptional regulator {ECO:0000313|EMBL:ADB08708.1};
GN OrderedLocusNames=BDP_0009 {ECO:0000313|EMBL:ADB08708.1};
OS Bifidobacterium dentium (strain ATCC 27534 / DSM 20436 / JCM 1195 / Bd1).
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=401473 {ECO:0000313|EMBL:ADB08708.1, ECO:0000313|Proteomes:UP000008693};
RN [1] {ECO:0000313|EMBL:ADB08708.1, ECO:0000313|Proteomes:UP000008693}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27534 / DSM 20436 / JCM 1195 / Bd1
RC {ECO:0000313|Proteomes:UP000008693};
RX PubMed=20041198; DOI=10.1371/journal.pgen.1000785;
RA Ventura M., Turroni F., Zomer A., Foroni E., Giubellini V., Bottacini F.,
RA Canchaya C., Claesson M.J., He F., Mantzourani M., Mulas L., Ferrarini A.,
RA Gao B., Delledonne M., Henrissat B., Coutinho P., Oggioni M., Gupta R.S.,
RA Zhang Z., Beighton D., Fitzgerald G.F., O'Toole P.W., van Sinderen D.;
RT "The Bifidobacterium dentium Bd1 genome sequence reflects its genetic
RT adaptation to the human oral cavity.";
RL PLoS Genet. 5:E1000785-E1000785(2009).
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DR EMBL; CP001750; ADB08708.1; -; Genomic_DNA.
DR AlphaFoldDB; D2Q6I6; -.
DR STRING; 401473.BDP_0009; -.
DR KEGG; bde:BDP_0009; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_0_11; -.
DR Proteomes; UP000008693; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06283; PBP1_RegR_EndR_KdgR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF138; HTH-TYPE TRANSCRIPTIONAL REGULATOR KDGR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000008693};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 10..65
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 339 AA; 37321 MW; 73960B25497D0AB7 CRC64;
MSANKAGRKA SMGDVAAAAG VSKTTISRYL HGEFGYMSEQ TKAKIEGVIK ELGYRPNKMA
QSLKATVSHM VGVSIADMGN PFSSLLIKGI QEECRARDVQ LLVSDSNNQP TLERANIESL
LDAQVDGLIV NTVGNNDDWL VRFHDRANRK PVVMLDRIVL PLIYDSVTNN NDAAVREMLE
YLKGQGFAYV VFVMRPGEGI STRTARRQAV ERYCDDLGLG GEVLVYDDGI DGLRSRIANL
LELCGNRKTC LFANNDESMR DILEATSAGL RRHVGVCSFA DEHWAKYSGP GITCLDQEPM
LMGRRAAQKL FARIYDGSEE PCSLDEVPAR LCIFASTEI
//
