ID   D2QAF3_BIFDB            Unreviewed;       868 AA.
AC   D2QAF3;
DT   02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   02-MAR-2010, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Helicase {ECO:0000313|EMBL:ADB09789.1};
GN   Name=helY {ECO:0000313|EMBL:ADB09789.1};
GN   OrderedLocusNames=BDP_1160 {ECO:0000313|EMBL:ADB09789.1};
OS   Bifidobacterium dentium (strain ATCC 27534 / DSM 20436 / JCM 1195 / Bd1).
OC   Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC   Bifidobacteriaceae; Bifidobacterium.
OX   NCBI_TaxID=401473 {ECO:0000313|EMBL:ADB09789.1, ECO:0000313|Proteomes:UP000008693};
RN   [1] {ECO:0000313|EMBL:ADB09789.1, ECO:0000313|Proteomes:UP000008693}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27534 / DSM 20436 / JCM 1195 / Bd1
RC   {ECO:0000313|Proteomes:UP000008693};
RX   PubMed=20041198; DOI=10.1371/journal.pgen.1000785;
RA   Ventura M., Turroni F., Zomer A., Foroni E., Giubellini V., Bottacini F.,
RA   Canchaya C., Claesson M.J., He F., Mantzourani M., Mulas L., Ferrarini A.,
RA   Gao B., Delledonne M., Henrissat B., Coutinho P., Oggioni M., Gupta R.S.,
RA   Zhang Z., Beighton D., Fitzgerald G.F., O'Toole P.W., van Sinderen D.;
RT   "The Bifidobacterium dentium Bd1 genome sequence reflects its genetic
RT   adaptation to the human oral cavity.";
RL   PLoS Genet. 5:E1000785-E1000785(2009).
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DR   EMBL; CP001750; ADB09789.1; -; Genomic_DNA.
DR   RefSeq; WP_012902151.1; NC_013714.1.
DR   AlphaFoldDB; D2QAF3; -.
DR   STRING; 401473.BDP_1160; -.
DR   GeneID; 69536665; -.
DR   KEGG; bde:BDP_1160; -.
DR   eggNOG; COG4581; Bacteria.
DR   HOGENOM; CLU_002902_4_1_11; -.
DR   Proteomes; UP000008693; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd18795; SF2_C_Ski2; 1.
DR   Gene3D; 1.10.3380.30; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR012961; Ski2/MTR4_C.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08148; DSHCT; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM01142; DSHCT; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ADB09789.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008693}.
FT   DOMAIN          62..220
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          319..518
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          278..309
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   868 AA;  98281 MW;  1893E998F38FFEFA CRC64;
     MTHHRHRRNG SMDITSTNAT VEPSPSQRYA MFKQTQRKQG MAATRFAQSM PFELDDFQME
     ANEALEADSN VLVAAPTGAG KTVVADFAIY LAQERNVKAF YTTPIKALSN QKYHDLVDQY
     GQDRVGLLTG DTSINSEADI VVMTTEVLRN MLYEHSMTLE ALRYVILDEV HYLADRFRGP
     VWEEVIIHLP QSVKIIGLSA TVSNVEDFSN WIVSVRGDTK LIVSEKRPVP LEQHVLVQAD
     DRTEPELIDL YRRDAHGDQT VKLNAQLLNR LDQLDRQAAR RQGAQRPERR KGKGKGPWHD
     RESSHKVERH TPKRWAVVDE LNFLDMLPGI YFIFSRNGCD QAVEQCINAG LELTSNGEVR
     RIRRIVDEMI DGQLSQEDLK ALHFSQFRFA LEEGFAPHHA GMIALFRQIV ERLFEEGLVK
     VVFATETLAL GINMPARCVV VEKLEKYDGT GHVGLTPGEF TQLTGRAGRR GIDTIGHAVV
     VDHRGFVPAT AAALSSKRVY PLHSSFRPTF NMAVNLLNSS DYETARITLD HSFAQWEANE
     SAWQLEAQMD TLKKALEGYE HAFTCEFGDF ADFMRLRMRL SELEKNERRR LKHEVFRTQS
     ERSQAFMDLD EKIAAMRELD RNHPCRKCPD LQQHLKWGHR WSREMRELER VRHRYESRTG
     SVARQFDHIC TVLEELGYLE RDSDKSRHAD YLLTERGQLL RHLYSELDLV LAQAIDEGAF
     DGLDAPELAS VLSSLIYEAR GGSGGEPRHY PGGIQGNVAV CAAQLRGVHA KIAMMCEDHA
     LEEPRQLDFG IADIVYEWAQ GESLSRVLYG TDLTGGDFVR NCKRLADVLQ QIAVAEPYLT
     KRAGTLALVA KQAMEAVNHG VVAYSGVD
//