ID   D2RT07_HALTV            Unreviewed;       466 AA.
AC   D2RT07;
DT   02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   02-MAR-2010, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   SubName: Full=Uracil-xanthine permease {ECO:0000313|EMBL:ADB60887.1};
GN   OrderedLocusNames=Htur_2003 {ECO:0000313|EMBL:ADB60887.1};
OS   Haloterrigena turkmenica (strain ATCC 51198 / DSM 5511 / JCM 9101 / NCIMB
OS   13204 / VKM B-1734 / 4k) (Halococcus turkmenicus).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC   Natrialbaceae; Haloterrigena.
OX   NCBI_TaxID=543526 {ECO:0000313|EMBL:ADB60887.1, ECO:0000313|Proteomes:UP000001903};
RN   [1] {ECO:0000313|EMBL:ADB60887.1, ECO:0000313|Proteomes:UP000001903}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51198 / DSM 5511 / JCM 9101 / NCIMB 13204 / VKM B-1734 /
RC   4k {ECO:0000313|Proteomes:UP000001903};
RX   PubMed=21304683; DOI=10.4056/sigs.681272;
RA   Saunders E., Tindall B.J., Fahnrich R., Lapidus A., Copeland A.,
RA   Del Rio T.G., Lucas S., Chen F., Tice H., Cheng J.F., Han C., Detter J.C.,
RA   Bruce D., Goodwin L., Chain P., Pitluck S., Pati A., Ivanova N.,
RA   Mavromatis K., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J.,
RA   Jeffries C.D., Brettin T., Rohde M., Goker M., Bristow J., Eisen J.A.,
RA   Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C.;
RT   "Complete genome sequence of Haloterrigena turkmenica type strain (4k).";
RL   Stand. Genomic Sci. 2:107-116(2010).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR   EMBL; CP001860; ADB60887.1; -; Genomic_DNA.
DR   RefSeq; WP_012943176.1; NC_013743.1.
DR   AlphaFoldDB; D2RT07; -.
DR   STRING; 543526.Htur_2003; -.
DR   GeneID; 8742602; -.
DR   KEGG; htu:Htur_2003; -.
DR   eggNOG; arCOG02805; Archaea.
DR   HOGENOM; CLU_017959_8_0_2; -.
DR   OrthoDB; 76842at2157; -.
DR   Proteomes; UP000001903; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR   InterPro; IPR006043; NCS2.
DR   InterPro; IPR006042; Xan_ur_permease.
DR   NCBIfam; TIGR00801; ncs2; 1.
DR   PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR   PANTHER; PTHR42810:SF4; URIC ACID TRANSPORTER UACT; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        25..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        58..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        102..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        140..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        170..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        199..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        329..350
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        356..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   466 AA;  47548 MW;  C103718173E11FB1 CRC64;
     MSNETDGGIQ IEYGVDDKPP LPKSILLGLQ HVAVMIVPAT AVAYVVANGV GLEADAAYLV
     QMVLLFSGLA TMVQAYTVGP VGARLPIVMG SSFTFVGATI DIGASFGMAA VFGAILVTGF
     VVEGLIGWQF KRIKPFFPPL VTGLVVVIIG LYLIPVAMDY AAGGVGASDF GALHHIGLAA
     LVLAIAVGLN MFTRGVTRLL SVLVAIVVGY AAAIALTVAT GLELVTFSAV GEAAWIELPS
     PTRFGFEFEP IAIATFAVLF LVSSMETVGD MSGVTAAEGR NPTDEEFRGG LFNDGLLSSI
     GSIFGAFPIT SFSQNVGIVN FTGVMSRHVV GIGGVFLAVL GLSPKVGAAV TTIPSAVFGG
     AVLLMAGMVA ASGFRLIVTH VDLDRRNTVI VATSIGLGLG VATTPDALAG LPSRAELFFG
     QPVIVTALSG LALNTFVPGP SSPLFDAVPE AGVGETESAT VDPTDD
//