ID D2RU49_HALTV Unreviewed; 502 AA.
AC D2RU49;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=L-lysine 6-monooxygenase (NADPH) {ECO:0000313|EMBL:ADB59118.1};
DE EC=1.14.13.59 {ECO:0000313|EMBL:ADB59118.1};
GN OrderedLocusNames=Htur_0217 {ECO:0000313|EMBL:ADB59118.1};
OS Haloterrigena turkmenica (strain ATCC 51198 / DSM 5511 / JCM 9101 / NCIMB
OS 13204 / VKM B-1734 / 4k) (Halococcus turkmenicus).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Haloterrigena.
OX NCBI_TaxID=543526 {ECO:0000313|EMBL:ADB59118.1, ECO:0000313|Proteomes:UP000001903};
RN [1] {ECO:0000313|EMBL:ADB59118.1, ECO:0000313|Proteomes:UP000001903}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51198 / DSM 5511 / JCM 9101 / NCIMB 13204 / VKM B-1734 /
RC 4k {ECO:0000313|Proteomes:UP000001903};
RX PubMed=21304683; DOI=10.4056/sigs.681272;
RA Saunders E., Tindall B.J., Fahnrich R., Lapidus A., Copeland A.,
RA Del Rio T.G., Lucas S., Chen F., Tice H., Cheng J.F., Han C., Detter J.C.,
RA Bruce D., Goodwin L., Chain P., Pitluck S., Pati A., Ivanova N.,
RA Mavromatis K., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J.,
RA Jeffries C.D., Brettin T., Rohde M., Goker M., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of Haloterrigena turkmenica type strain (4k).";
RL Stand. Genomic Sci. 2:107-116(2010).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- PATHWAY: Siderophore biosynthesis. {ECO:0000256|ARBA:ARBA00004924}.
CC -!- SIMILARITY: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-
CC oxygenase family. {ECO:0000256|ARBA:ARBA00007588}.
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DR EMBL; CP001860; ADB59118.1; -; Genomic_DNA.
DR RefSeq; WP_012941446.1; NC_013743.1.
DR AlphaFoldDB; D2RU49; -.
DR STRING; 543526.Htur_0217; -.
DR GeneID; 8740780; -.
DR KEGG; htu:Htur_0217; -.
DR eggNOG; arCOG07945; Archaea.
DR HOGENOM; CLU_020931_0_0_2; -.
DR OrthoDB; 224622at2157; -.
DR Proteomes; UP000001903; Chromosome.
DR GO; GO:0047091; F:L-lysine 6-monooxygenase (NADPH) activity; IEA:UniProtKB-EC.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR025700; Lys/Orn_oxygenase.
DR PANTHER; PTHR42802:SF1; L-ORNITHINE N(5)-MONOOXYGENASE; 1.
DR PANTHER; PTHR42802; MONOOXYGENASE; 1.
DR Pfam; PF13434; Lys_Orn_oxgnase; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Monooxygenase {ECO:0000313|EMBL:ADB59118.1};
KW Oxidoreductase {ECO:0000313|EMBL:ADB59118.1}.
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 502 AA; 56617 MW; AC614D9256BC785B CRC64;
MTEEDRTISV VDGDDATTGD DASEPVVDRG HYDVLGVGLG PFNLGLAALL DGAESDCDLE
AVFLEREPEF AWHEGMLIEG ATLEVPFLAD LVTMADPTNP YSFLNYVRER DRIYEFYFYE
TFQIPRREYD DYLRWVAETV PTTQFEREVT SVEYETADAG DERGGANGTA DDGTFVVEAV
VPETGQRYRY RADDLVMGVG SRPALPEFAR DHADGDAPLF HTADYLERRA DVLEADSITV
VGSGQSAAEV VLDLLERQSD NGFRLDWLTR SDGFFPMEYS KLGLQHFTPE YTEYFYDLPQ
SRKDELLPDQ DLLYKGIDPE TSERIYDTLY ERSIGDRDPD FGMLATTAVR DIERVDGSYW
LECEHRQQEE AFALETDAVI FGTGYQRPTP TFLEPVADRI AFDDRGRFRV SEDYRLEGDL
GGADDDGGRV FVQNAEMHTH GVGTPDLGLG CYRNAVIIER LAGREVYPVD RDTVFQDFDV
DQFADHAPVR TDAPRSLTPD TE
//
