ID D2RYL2_HALTV Unreviewed; 960 AA.
AC D2RYL2;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=Htur_1021 {ECO:0000313|EMBL:ADB59913.1};
OS Haloterrigena turkmenica (strain ATCC 51198 / DSM 5511 / JCM 9101 / NCIMB
OS 13204 / VKM B-1734 / 4k) (Halococcus turkmenicus).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Haloterrigena.
OX NCBI_TaxID=543526 {ECO:0000313|EMBL:ADB59913.1, ECO:0000313|Proteomes:UP000001903};
RN [1] {ECO:0000313|EMBL:ADB59913.1, ECO:0000313|Proteomes:UP000001903}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51198 / DSM 5511 / JCM 9101 / NCIMB 13204 / VKM B-1734 /
RC 4k {ECO:0000313|Proteomes:UP000001903};
RX PubMed=21304683; DOI=10.4056/sigs.681272;
RA Saunders E., Tindall B.J., Fahnrich R., Lapidus A., Copeland A.,
RA Del Rio T.G., Lucas S., Chen F., Tice H., Cheng J.F., Han C., Detter J.C.,
RA Bruce D., Goodwin L., Chain P., Pitluck S., Pati A., Ivanova N.,
RA Mavromatis K., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J.,
RA Jeffries C.D., Brettin T., Rohde M., Goker M., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of Haloterrigena turkmenica type strain (4k).";
RL Stand. Genomic Sci. 2:107-116(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001860; ADB59913.1; -; Genomic_DNA.
DR RefSeq; WP_012942224.1; NC_013743.1.
DR AlphaFoldDB; D2RYL2; -.
DR STRING; 543526.Htur_1021; -.
DR GeneID; 8741608; -.
DR KEGG; htu:Htur_1021; -.
DR eggNOG; arCOG02352; Archaea.
DR eggNOG; arCOG02358; Archaea.
DR eggNOG; arCOG02359; Archaea.
DR eggNOG; arCOG02369; Archaea.
DR eggNOG; arCOG03567; Archaea.
DR HOGENOM; CLU_009094_0_0_2; -.
DR OrthoDB; 106630at2157; -.
DR Proteomes; UP000001903; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR025847; MEDS_domain.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF14417; MEDS; 1.
DR Pfam; PF08447; PAS_3; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:ADB59913.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000313|EMBL:ADB59913.1}.
FT DOMAIN 672..724
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 742..955
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 712..739
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 960 AA; 107963 MW; 0E8F1BAD72B7D205 CRC64;
MSQQGERSDQ PGTPGLESGL EALRQSPEFR GPVESLDGHD HANDHFALIY KNRDEQFAAA
IPFIRQGLEQ GERCLYVADD NSKAEVLEAM RARGIDVDGA LDSGALSVHT EADTYRRTGT
FNQDAILEFW EDSLTEATDE DGYTGIRAAT EMTWALDENT SPDQLVEYEA ALNSLFQNED
YTVMCQYNRE RFPPEVLEDV IQTHPLLIHD NVISHNVYYT PPEEVFGPEQ PADRVDRMMG
TLRERTEAKT ELQRSKEHEQ AQQRLYEIVA DSDLPFDDKL QAVLELGCER FDLEYGGIAR
IDPATDLFEV ETIRGDHDHL VPGEQYPLSE TYCRSVADDG ETAVVTDPVS EGFEGKLCYE
RFGVQTYLGT RLEVDGDDDR TFFFASNEPR EEGFSEAERT FHHLMGQWVE YELERRQAAE
ALREQTHTLE TINQVGNSLA AELDLENLVQ KVTDAGTEIT GAEFGAFFYN VIDDQGESYT
LYTLSGVPDE AFEDFPMPRN TEVFGPTFHG EGVVRSDDIT NDPRYGNNAP YNGMPEGHLP
VCSYLAVPVI SNSGEVHGGL FFGHSEPGVF TEKDENIITG ISAQAAVAID NARLYETARE
SEQRFRALVT ASSEAVFRMG PDWDEMQHLE AQGFLADTNE PTSDWLDKYI HPNDQERVME
AVNEAVRTKS TFELEHRVEQ VDGSLGWSFT RAVPMLNEDG DIEEWIGMAS DVTERKRRQQ
ELEQTNAQLE RSNAELKRFA YAASHDLQEP LRMVSSYVQL LEQRYADDLD ADAQEYIEFA
VDGADRMREM IDALLQYSRL NTSDKEFEPV DCNDVLAQAT DNLQIAIEES SAEITSDSLP
TVMGDEQQLV QLFQNLLDNA ITYAGDEPPH IHVTAEKQND EWVLSVQDNG IGIGSEKAEE
IFEVFNRLHT TDEYAGTGIG LALCQRIVDI HNGRIWVESE LGEGSTFSFT VPEKKASKSA
//
