ID D2U8F8_XANAP Unreviewed; 505 AA.
AC D2U8F8;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Putative tryptophan halogenase protein {ECO:0000313|EMBL:CBA14592.1};
GN OrderedLocusNames=XALc_0046 {ECO:0000313|EMBL:CBA14592.1};
OS Xanthomonas albilineans (strain GPE PC73 / CFBP 7063).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Xanthomonas.
OX NCBI_TaxID=380358 {ECO:0000313|EMBL:CBA14592.1, ECO:0000313|Proteomes:UP000001890};
RN [1] {ECO:0000313|EMBL:CBA14592.1, ECO:0000313|Proteomes:UP000001890}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GPE PC73 / CFBP 7063 {ECO:0000313|Proteomes:UP000001890};
RX PubMed=20017926; DOI=10.1186/1471-2164-10-616;
RA Pieretti I., Royer M., Barbe V., Carrere S., Koebnik R., Cociancich S.,
RA Couloux A., Darrasse A., Gouzy J., Jacques M.A., Lauber E., Manceau C.,
RA Mangenot S., Poussier S., Segurens B., Szurek B., Verdier V., Arlat M.,
RA Rott P.;
RT "The complete genome sequence of Xanthomonas albilineans provides new
RT insights into the reductive genome evolution of the xylem-limited
RT Xanthomonadaceae.";
RL BMC Genomics 10:616-616(2009).
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DR EMBL; FP565176; CBA14592.1; -; Genomic_DNA.
DR RefSeq; WP_012914611.1; NC_013722.1.
DR AlphaFoldDB; D2U8F8; -.
DR STRING; 380358.XALC_0046; -.
DR GeneID; 57875421; -.
DR KEGG; xal:XALC_0046; -.
DR PATRIC; fig|29447.3.peg.48; -.
DR eggNOG; COG0446; Bacteria.
DR OrthoDB; 462203at2; -.
DR Proteomes; UP000001890; Chromosome.
DR GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR006905; Flavin_halogenase.
DR InterPro; IPR033856; Trp_halogen.
DR PANTHER; PTHR43747; FAD-BINDING PROTEIN; 1.
DR PANTHER; PTHR43747:SF4; FLAVIN-DEPENDENT TRYPTOPHAN HALOGENASE; 1.
DR Pfam; PF04820; Trp_halogenase; 1.
DR PIRSF; PIRSF011396; Trp_halogenase; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|PIRSR:PIRSR011396-2};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR011396-2};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR011396-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000001890}.
FT ACT_SITE 79
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-1"
FT BINDING 14..17
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT BINDING 79
FT /ligand="7-chloro-L-tryptophan"
FT /ligand_id="ChEBI:CHEBI:58713"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT BINDING 189
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT BINDING 337
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT BINDING 346
FT /ligand="L-tryptophan"
FT /ligand_id="ChEBI:CHEBI:57912"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT BINDING 350
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
SQ SEQUENCE 505 AA; 55504 MW; A289BD5A7F4322ED CRC64;
MIAAPLRNLV IVGGGTAGWM AAAALARMLG ADNRITVIES EQIGTVGVGE ATVPHIKAFN
TLLGINEAEF VRDTQGSFKL GIEFVDWLRP GIAYVHGFGS EIGHRLGLLP FQQYWFKQAL
AGKASPLGDY TLNTVAAKRG KFMTAASDVP PNSPLANIAY AYHFDAALYA QFLRRYAEQR
GVIRYEGIVE QVLLHPESGD VASVRLVSGE VIAGDLFIDC SGFRGLLIEQ ALHTGYHDFS
HCLPCDRALA VPCAKIGPPT PYTRATARAA GWQWRIPLQH RTGNGYVYSS AHVSDDEAAA
TLLANLDGPA LAEPRPLRFV TGRRKQAWNR NVIALGLASG FMEPLESTSI HLIQSGISKL
LELFPREGIS PVLVQRYNER IAFEFDRIRD FLVLHYHASE RADSAFWQQC RGMSIPAELQ
ATLDLFRDSG RFYRNGEEMF AEISWVQVMV GQGILPRAYH PLVDQVPVAD LERFMLSVAQ
TIGHCADAMP PHQAFIDRYC AAAPG
//
