ID D2UCS9_XANAP Unreviewed; 10708 AA.
AC D2UCS9;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Probable non-ribosomal peptide synthetase protein {ECO:0000313|EMBL:CBA15571.1};
GN OrderedLocusNames=XALc_1056 {ECO:0000313|EMBL:CBA15571.1};
OS Xanthomonas albilineans (strain GPE PC73 / CFBP 7063).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Xanthomonas.
OX NCBI_TaxID=380358 {ECO:0000313|EMBL:CBA15571.1, ECO:0000313|Proteomes:UP000001890};
RN [1] {ECO:0000313|EMBL:CBA15571.1, ECO:0000313|Proteomes:UP000001890}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GPE PC73 / CFBP 7063 {ECO:0000313|Proteomes:UP000001890};
RX PubMed=20017926; DOI=10.1186/1471-2164-10-616;
RA Pieretti I., Royer M., Barbe V., Carrere S., Koebnik R., Cociancich S.,
RA Couloux A., Darrasse A., Gouzy J., Jacques M.A., Lauber E., Manceau C.,
RA Mangenot S., Poussier S., Segurens B., Szurek B., Verdier V., Arlat M.,
RA Rott P.;
RT "The complete genome sequence of Xanthomonas albilineans provides new
RT insights into the reductive genome evolution of the xylem-limited
RT Xanthomonadaceae.";
RL BMC Genomics 10:616-616(2009).
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- PATHWAY: Siderophore biosynthesis. {ECO:0000256|ARBA:ARBA00004924}.
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DR EMBL; FP565176; CBA15571.1; -; Genomic_DNA.
DR STRING; 380358.XALC_1056; -.
DR KEGG; xal:XALC_1056; -.
DR eggNOG; COG1020; Bacteria.
DR Proteomes; UP000001890; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 8.
DR CDD; cd17643; A_NRPS_Cytc1-like; 1.
DR CDD; cd12117; A_NRPS_Srf_like; 1.
DR CDD; cd19544; E-C_NRPS; 3.
DR CDD; cd19531; LCL_NRPS-like; 7.
DR Gene3D; 3.30.300.30; -; 10.
DR Gene3D; 3.40.50.980; -; 18.
DR Gene3D; 1.10.1200.10; ACP-like; 9.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 10.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 10.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 10.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 10.
DR Pfam; PF13193; AMP-binding_C; 9.
DR Pfam; PF00668; Condensation; 10.
DR Pfam; PF00550; PP-binding; 10.
DR SMART; SM00823; PKS_PP; 10.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 10.
DR SUPFAM; SSF47336; ACP-like; 10.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 20.
DR PROSITE; PS00455; AMP_BINDING; 10.
DR PROSITE; PS50075; CARRIER; 10.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 10.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001890}.
FT DOMAIN 992..1067
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2057..2131
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 3140..3215
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 4203..4278
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 5265..5339
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 6356..6431
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 7421..7495
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 8499..8574
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 9562..9637
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 10615..10690
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 10708 AA; 1166914 MW; B5D14C15DF108BE8 CRC64;
MAESDPAAEE SIPPRDDDAA LPLSYAQQRL WFLEQLDQRA ARAYLLAGGV DLHGVLNLSA
LQQALDRIVA RHEALRTCFV ANDDGATQVI APANVGFALE CIDLRQTADP HADAQLHAEQ
ETNTPFDLSR GPLIRGRLLQ LADQQHRLLV TMHHIVSDGW SMALLVQELS ALYAAFVQGQ
PDPLPPLPIQ YPDYAMWQRR WLDGPLLQRQ LGLWREHLHD APALLELPTD HPRPALQDYR
GDHVDIVIDA ELTDALNHLS QRHSTTMFMT VLAGWAVLLS RLSGQDQVVI GAPVANRTRS
ELEALIGFFV NAQALRIDLR GAPTVADLLA QVRSTALAAQ DHQDVPFEQV IEALNPERSL
SAHPVFQVML TWQNTPTATP TLPGLELRSI VYPDTSAKFD LQLTLEAHDG RIVGTLGYAT
ALFERSTIER HLHHFFAVLH GMVADEHCRV ERLPLFNTTE RQQWLQRLAR EHRVFADQRC
LPSVFEQQVA RTPQAIAVVD GQCTLCYADL DARANQLAHH LIAHGIGPED RIALFLHRGV
EVIVAILAVL KAGAAYLPLD PAYPAERLAF MLDDAQPRVL ITQHALANAW QERDDITLLR
IDTDTDTWAQ HPTHAPQRTD LLPQHPAYLI YTSGSTGTPK GVVIAHAQVV RLLHATRACV
APTAEDVWTL FHSCAFDFSV WELWGALAHG GRLVVVSQDT ARDPDAFHTL LCEQRVSVLN
QTPSAFQALI DAQQHSDLQH HLRLVIFGGE ALQPASVSAW FTAHGQRTTL LNMYGITETT
VHVTAHALTA QDVQRPGNSP IGAPLADLRA YVLGPDGQCL PVGVAGELYV AGAGLARGYL
HRPALTAERF VPDPFADQPG TRMYRSGDLA RWRADGTLEY LGRNDEQIKL RGFRIELGEI
QAALHACDGV RQAAVIVRED DGDRRLIAYV VADAVASAEQ LRATLATRLP EHMVPAAYVQ
LDRLPLTPNG KLDRKALPAP DADALATQAY LAPEGERETQ LADLYRELLG VEQVGRHDNF
FALGGHSLLG VRLISRIRSA LGLELPLATL FAQPRLVDLA QALDNTDAST LPAIVPADRD
APLALSYAQQ RLWFLEQLDQ RAARAYLLAG GVDLHGVLNL SALQQALDRI VARHEALRTC
FVANDDGATQ VIAPANVGFA LECIDLRQTA DPHADAQLHA EQETNTPFDL SRGPLIRGRL
LQLAEQQHRL LVTMHHIVSD GWSMALLVQE LSALYAAFVQ GQPDPLPPLP IQYPDYAVWQ
RRWLDGPLLQ RQLSFWREHL HGAPALLELP TDHPRPALQD YRGDHVDIVI DAELTDALNH
LSQRHGTTMF MTVLAGWAVL LSRLSGQDQV VIGAPVANRT RSELEALIGF FVNAQALRID
LRGAPTVADL LAQVRVTALA AQDHQDVPFE KVIEALNPER SLSAQPVFQV VLTWQNVPDA
ELVLPDIRLQ PIPAQAGDAK FDLEFSLLEQ QDRIVGSLGY AKALFERSTI ERHLAQFVTL
LRGMVADAHV RVAQLPLLPA AERAQLQRFT VTESTSLPPA TCIHHLFDAQ VRRTPDAIAV
SEGQRTLRYA ELDARANRLA QRLRRSGVGL ESRVALYLPR SIEQVVAVLA TLKAGAAYVP
LDPELPSERL AFLLEDSRPR AVLTCTDLQD HLPASRAMLR VSVLTMDDIA ETQHDDPGAP
DVPCLCPDNL AYVIYTSGST GQPKGTLLTH AGAAHYLQWA IETYRPQPSA VVSSSLSFDA
TLTSLLAPLL CGAQVELLPD HDTLDALRQR LCDPTPLGLV KLTPAHLEVL GQQLADHPTP
LSPSVMVIGG EALPTTTLAR WQTLAPHTRL INEYGPTETV VGCAVHTTTA DDAHASNGRV
PIGQPIAHLR LYVLDAHGQH APIGVAGHLH IAGPQLARGY LGRADLTAER FVPDPFAEQP
GQRMYRSGDI TCWRPDGTLD YLGRNDDQVK LRGFRIELGE IAAALRACAG VQDAAVVLRE
DNPGEPRLVA YLVGDVDGIA LSPEAMRTQL DVRLPDYMLP TAYVQLETLP LTANGKLDRK
ALPAPDAAAY AARAYEAPQG AIEQTIAAIW GDLLGLETIG RHDNFFALGG HSLLAVTLTE
RMRQQGLRAD LRTLFATPTL AALAAASDAV SVNVPPNQIA SDSAVITPEM LPLVTLTQEQ
IDSIVAIIPG GSANLQDIYP LAPLQEGIFF HHLLQRQGDA YLQPNLIAFD SRSRLDGFID
ALQRVIDRHD ILRTAVAWEG LAAPVQVVWR RAALVIEHLC LDEADGEVAA QLQSRFDPRH
WRLDVRQAPL MRGVAAQDPA NGRWLLQLLC HHLALDHTTL EIVLEEVRCH LGGEADSLPA
PLPFRNFVAQ ALLGVSREEH EAYFRAMLSD VEEPCAPFGV VNVQGDGADV EEARLELPDP
LSALLRDQAR VLGVSAASLF HLAWAQVVAR ATGCETVVFG TVLFGRMQGG TGADRALGVF
INTLPLRIEI DASNVAESVR MVQQRLAGLL RHEHAPLSLA QRCSGVPAPA PLFTSLLNYR
HGVQAEDTAE AMAWEGIQTL SSHERTNYPL AVSIDDVGSG FTVNVQSQHP LVPGRIGAFL
MQALTGLVDA LVHAPEKRVR DLDVLPEAER HQVLTQWNAT AVDYPRDAYV HELFEAQVAR
TPSAIALVQG QVSLTYGELN TQANRMAHYL RELGVRPDDR VAICAQRSVE MVVALLAVLK
AGSAYVPLDP AYPPERLAYM RADCGALTVL TDTASRHLVE DSVASAVIVD LQADSKCWEH
LPDSNPDRHA SGLTARHLAY VIYTSGSTGA PKGAMNEHRS VVNLALAQIR AFNVEENSRV
MQFSSLSFDA FASELFVSLL CGASLYIADR DAVLAGETLT KILNEHQISH VTLPPSVLNN
LPEKPAFSCL KTLVVAGEAL SASIVERWGQ GRRLINAYGP TETTVCACLH ECDASMTGAP
PIGRPIANVR IYILDAHIAP VPIGVAGELY IGGDGVARGY LNRDDLTVER FLPDPFSADP
TARMYRTGDL GRWRADGTIE FVGRNDHQVK IRGFRIELGE IEARLSAHAE VRECVVVALD
AVTSSDKRLV AYWVGAEGVI SEHLGAETLR SWLTDVLPDY MVPAAYVRLD RLPLTPNGKL
DRKALPAPDG SAYAAHAYEA PQGEIEQTIA AIWSELLGLE NIGRHDNFFA LGGHSLLGVR
LISRIRSALG LELPLATLFA QPRLVDLAQA LDNTDASTLP AIVPADRDAP LPLSYAQQRL
WFLEQLDQRA ARAYLLAGGV DLHGALNLPA LQQALDRIVA RHEALRTCFV TDDDGATQSI
APADVGFALT CADLRNTPDA QVAAQDQAEQ ETNTPFELSR APLIRGRLLQ LAEQQHRLLV
TMHHIISDGW SIGILLRELG ALYAAFVQGQ PDPLPPLPIQ YPDYAVWQRR WLDGPLLQRQ
LGFWREHLHS APALLELPTD HPRPALQDYR GDHVDITLDT ALTHALRALS QRHGTTVFMT
VLTGWAVLLS RLSGQDQVVI GAPVANRTRS ELEALIGFFV NAQALRIDLR GAPTVADLLA
QVRATALAAQ DHQDVPFEQV IEALNPERSL SAQPVFQVVL TWQNVPDAEL ILPDIRLQPI
PAQASDAKFD LEFSLHEQQD RIVGSLGYAT ALFERSTLER HLAQFVTLLR GMVTDAHVRV
AQLPLLPADE RVQLQRFTVT ESTSLPPATC IHSLFEAQVQ RTPDAIAVSE GEHTLRYAEL
DGCANRLAQR LRRSGVGVES RVALYLPRSI EQVVAVLATL KAGAAYVPLD PELPSERLAF
LLEDSRPRAV LTCTNLQDHL PASRAMLRVS VLTLDDIADT HHDDPSAPDV PGLCPDNLAY
VIYTSGSTGQ PKGTLLTHAS AAHYLQWAVA TYRPTPSAVV SSSLSFDATL TSLIAPLLCG
AQIELLPEHD TLDALRQRLC DPTPLGLVKL TPAHLDVLGQ QLADHSTPLT PAVMVIGGEA
LPPATLARWH ALAPHTRLIN EYGPTETVVG CAVHTTTADD AHAPNGRVPI GQPIAHLRLY
VLDAHGQHAP IGVAGELHIA GPQLARGYLG RADLTAERFV PDPFAEHPGQ RMYRSGDIAC
WRADGTLEYL GRNDDQVKLR GFRIELGEIA AALRACAGVQ DAVVLLREDT PGEPRLVAYV
VGNADVHSAE RLRSQLANRL PEVMLPTAYV HLEALPLTAN GKLDRKALPA PDGTAYAARA
YEAPQGAIEQ AIAAIWGDLL GLETIGRHDN FFALGGHSLL AVRVASRLRH ELGTEIGVAE
LFTHTTLQQL AACVASSSAS VLPPITPLEP DAPRMLSFAQ QRLWFLSQFE GVSQAYHISG
GLRLRGALDT QALQHALDRI VARHASLRTS FALVDGQALQ QIAAEDSGFQ LIAHDLCDVQ
DRETALERLL ADEAQTPFAL ECGPLIRGVL VQLAHDEHVL FVTMHHIVSD GWSMGILINE
LSVLYRAFAR GEADPLSPLS IQYADYAHWQ RQWLTGEVLQ RQAAYWREAL SGAPVLLELP
TDRPRPAQQD HAGAMLEVVI GPQQAQALKA LSQRHGLTLY MTLLASWALL LSRLSGQGDV
VIGSPAANRG RSETEGLIGF FVNTLALRVE LSGSPTLAQL LASVKERALQ AQAHQDIPFE
QVVELVQPPR SLAHAPLFQV MFAWQNTPQG ELDLAELEAS GLGTAQTSAQ FDLALALAES
EDGILGSLNY ATALFERSTL DRWIGHWQHL LNAMVAEGAE DQAVDHLPLL SEDERYQVLM
QWNATASDYP RDACVHELFE AQVARDPSAI AVVQGEVSLT YGELNAQANQ LAHYLRELGV
CPDDRVAICV QRSVEMVVAL LAVLKAGGAY VPLDPAYPPE RLAYMRADCG AVAVLTDAAS
RHLVEDSATT AVIVDLQADG ERWEHLPDLN LDHHASGVTA HHLAYVIYTS GSTGTPKGAM
NEHRSVVNLA LAQIRAFNVE ENSRVMQFSS LSFDAFASEL FVSLFCGASL HIADRGAVLA
GETLTKILSE HQISHVTLPP SALNNLPEKP ELSCLKTLVV AGEALSAGIT ERWGQGRRLI
NAYGPTETTV CACMHECDAS ITGAPPIGRP INNVRIYILD VHGAPVPIGV AGELYIGGDG
VARGYLNRDD LTVERFLPDP FSADPTARMY RTGDLGRWRA DGTIEFLGRN DHQVKIRGFR
IELGEIEARL SAHAEVRECV VVALEDATGT GKRLVAYWVG AEGVRSDSVD ADALRSWLTD
VLPDYMVPAA YVQLDRLPLT PNGKLDRKAL PAPDVTAYAA HAYEAPQGEI EQTIAAIWRE
LLGLENIGRH DNFFALGGHS LLAVTLAERM RQQGLQADLR SLFATPTLAA LAAASGAVSV
SVPPNQIAPD SVAITPEMLP LVALTQAQID TIVAMTPGGP ANLQDIYPLA PLQEGIFFHH
LLQREGDAYL LRNLIAFDSR SRLDGFVDAL QRVIDRHDVL RTAVVWEGLT APVQVVWRRA
ALVIEHVCLD ESDGEVAAQL QSRFDPRHWR LDLRQAPLMR GFAAHDLANG RWLLQLMSHQ
LTSDHTTLAI LLDEVKQHLG GHSDRLPPAL PFRNFVAQAL LGVSQDEHDA YFRTMLGDVA
EPCAPFGLLN AQGDGSDVEE LRFELPDPLS ALLRKQARVL GVSVASLFHL AWAQVVARAT
GRESVVFGTL LFGRMQSGTG GDRTLGMFIN TLPLRIEIDG SSVAKSVRLA QQHLAELLRH
EHAPLSLAQR CSRVPAPAPL FTSLLNYRHT APAESSAESL AWEGIETLVE NDRTSYPLMV
SIDDLGSDFG LTVQSQRPLV PGRIGAFLMK ALEGLVDALA HAPETAVRDL DVMPEAERHQ
ILMEWNATAA DYPRDACVHE LFEAQVARDP AAIAVMQGEV ALTYGELNAQ ANQLAHYLRA
LGVRPDDRVA ICIQRSVEMV VALLAVLKAG GAYVPLDPAY PPERLAYMLT DCGATVVLTD
TGSRYLVEGS PASDVIVDLQ TDGERWAYLP NRNPDRNASD LTARHLAYVI YTSGSTGVPK
GAMNAHRGVV NRLVWMQDAY KLDQSEIVLQ KTPISFDVSV WEVFWPLLSG ARVQLAEPEG
HKDPVYLKAL IRDAHITTLH FVPSMLRALI EHGDHAPFPE IRRVICSGEA LPPTLAERAQ
ATFPAAGIFN LYGPTEAAVD VTAWRYHVGW GHASNLPIGR PIANTQIYIL DSHGAPVPIG
VVGELYIGGD GVGRGYLNRD DLTAERFIAD PFSETANARM YRSGDLARWR ADGTIEFLGR
NDHQVKIRGF RIELGEIEAR LSAHAEVREC VVVALEDATG TGKRLVAYWV GAEGVRSDSV
DADALRSWLT DVLPDYMVPA AYVQLDRLPL TPNGKLDRKA LPAPDVTAYA AHAYEAPQGE
IEQTIAAIWR ELLGLENIGR HDNFFALGGH SLLGVRLISR IRSALGLELP LATLFAQPRL
VDLAQALDNT DASTLPAIVP ADRDAPLPLS YAQQRLWFLE QLDQRAARAY LLAGGVDLHG
VLNLSALQQA LDRIVARHEA LRTCFVANDD GATQVIAPAN VGFALECIDL RQTADPHADA
QLHAEQETNT PFELSRGPLI RGRLLQLAEQ QHRLLVTMHH IVSDGWSMAL LVQELSALYA
AFVQGQPDPL PPLPIQYPDY AMWQRRWLDG PLLQRQLGFW REHLHDAPAL LELPTDHPRP
AVQDYRGDHV DIVIDAELTD ALRALSQRHG TTVFMTVLAG WAVLLSRLSG QDQVVIGAPV
ANRTRSELEA LIGFFVNAQA LRIDLRGAPT VADLLAQVRS TALAAQDHQD VPFEKVIETL
NPERSLSAQP VFQVVLTWQN VPDAELVLPD IRLQPIPAQA GDAKFDLEFS LHEQQDRIVG
SLGYATALFE RSTIEHHLAQ FVTLLRGMVA DAHVRVAQLP LLPAAERTQL HRFTVTETAP
LTPATCIHHL FQAQVQHTPD AIAVSEGQRT LRYAELDARA NRLAQRLRRS GVGLESRVAL
YLPRSIEQVV AVLATLKAGA AYVPLDPELP SERLAFLLED SRPRAVLTCT DLQDHLPASR
AMLRVSVLTL DDIADRQHDD PGAPDVPGLC PDNLAYVIYT SGSTGQPKGT LLTHAGAAHY
LQWAIETYRP QPSAVVSSSL SFDATLTSLL APLLCGAQVE LLPDHDTLDA LRQRLCDPTP
LGMVKLTPAH LEVLGQQLAD HPTPLNPAVM VIGGEALPPA TLARWQALAP HTRLINEYGP
TETVVGCSVH TTTADDAHAS NGRVPIGQPI AHLRLYVLDA YGQHAPMGVA GELHIAGPQL
ARGYLGRADL TAERFVPDPF AEQPGQRMYR SGDIACWRAD GTLEYLGRND DQVKLRGFRI
ELGEIAAALR ACAGVQDAVV LLREDHPGEP RLVAYLVGDV DGIALSPEAV RTQLDVCLPD
YMLPTAYVQL ETLPLTANGK LDRKALPAPD AAAYAAHAYE APQGAIEQTI AAIWSDLLGL
ETIGRHDNFF ALGGHSLLAV TLTERMRQQG LRADLRTLFA TPTLAALAAA SDAVSVNVPP
NQIASDSAVI TPEMLPLVTL TQEQIDSIVA IIPGGSANLQ DIYPLAPLQE GIFFHHLLQR
QGDAYLQPNL IAFDSRSRLD GFIDALQRVI DRHDILRTAV AWEGLAAPVQ VVWRRATLVI
EHLCLDEADG EVAAQLQSRF DPRHWRLDVR QAPLMRGVAA QDPANGRWLL QLLCHHLALD
HTTLEIVLEE VRCHLGGDAD SLPAPLPFRN FVAQALLGVS REEHEAYFRA MLSDVEEPCA
PFGVVNVQGD GADVEEARLE LPDPLSALLR DQARVLGVSA ASLFHLAWAQ VVARATGCET
VVFGTVLFGR MQGGTGADRA LGVFINTLPL RIEIDRSNVV ESVRMVQQRL AGLLRHEHAP
LSLAQRCSGV PAPAPLFTSL LNYRHGVQAE DAAEAMAWEG IQTLSIQTRT NYPLTVSIDD
VGSGFTVNVQ SQHPLVPGRI GAFLMQALAG LVDALVHAPE TGVRDLDVLP EAERQQVLTQ
WNATAVDYPR DACVHELFES QVARTPSAIA LVQGEVSLTY GELNARANRL AHYLCALGVR
PDDRVAICLE RGITAIVAML GVLKAGAAYL SLDPALPDRR LHDLLDDCRA CAVVVDQTLP
AALRDGLTQP TIALANLAIT PESARNPEIA GLGPQHLAYV MYTSGSTGRP KAVMIPHQGL
VGYTAALTER CALQAGDISL VFTSLHFDLA LTGVYPPLLC GATVQLCAHD STPAQWAHAL
RQGRGIAPLK LTPSHLALLQ QELGDTPLDG CVRVLVLGGE ALSADAVRWW RARSPSTQIF
NHYGPTETTV GCLMHGLGED EERIPLGRPL TGVRVYVLDA HAQLCPHGVA GELYIAGAQL
ARGYLGRADL TAERFVPDPF AEHPGARMYR SGDLARWRVD GTLDYLGRND NQVKLRGFRI
ELGEIAAALR TCTSVQDAVV LLREDTPGEP RLVAYVISDA DAHNAQSLRS QLANRLPEVM
LPNAYVHLET FPLTPNGKLD RKALPAPDAD ALATQAYLAP EGERETQLAD LYRELLGVEQ
VGGHDNFFAL GGHSLLGVRL ISRIRSTLGL ELPLATLFAQ PRLADLAQAL DNVATSTLPA
IVQTERNAPL PLSFAQQRLW FLQQLDERAG LAYLMPGGVD LHGVLNLSAL QQALDRIVAR
HEALRTCFVA NDDGATQVIA PANVGFALEC IDLRQTADPH ADAQLHAEQE TNTPFDLSRG
PLIRGRLLQL AEQQHRLLVT MHHIVSDGWS MALLVQELSA LYAAFVQGQP DPLPPLPIQY
PDYAVWQRRW LDGPLLQRQL GFWREHLHGA PALLELPTDH PRPALQDYRG DSVDIVIDAE
LTDALRALSQ RHGTTVFMTV LAGWAVLLSR LSGQDQVVIG APVANRTRSE LEALIGFFVN
AQALRIDLRG APTVADLLAH VRSTALAAQD HQDVPFEKVI ETLNPERSLS AQPVFQVVLT
WQNVPDAELV LPEIRLQPIP AQAGDAKFDL EFSLHEQQDR IVGSLGYATA LFERSTIERH
LAQFVTLLRG MVANAHVRVA QLPLLPAAER TQLQRFTVTE TAPLTPATCI HHLFQAQVRR
TPDAIAVREG THTLRYAELD ARANRLAQRL RRSGVGLESR VALYLPRSIE QVVAVLATLK
AGAAYVPLDP ELPSERLAFL LQDSRPHAAL TCSDLRTQLQ SNSGLHTVSV LILDDIADTQ
HDDPGAPDIP GLCPDNLAYV IYTSGSTGQP KGTLLTHAGT AHYLQWAIAT YRPTPSAVVS
SSLSFDATLT SLLAPLLCGA QVELLPDHDT LDALRQRLCD PTPLGMVKLT PAHLEVLGQQ
LADHPTPLNP AVMVIGGEAL PPATLARWQA LAPHTRLINE YGPTETVVGC AVHTTTADDA
HASNGRVPIG QPIAHLRLYV LDAYGQHAPI GVAGELHIAG PQLARGYLGR PDLTAERFVP
DPFAEQPGQR MYRSGDIACW RPDGTLDYVG RNDDQVKLRG FRIELGEIAA ALRACAGVQD
AVVLLREDHP GEPRLVAYVV GDADVHSAER LRSQLANRLP EAMLPTAYVH LETLPLTANG
KLDRRTLPAP DADARVMQAY VAPEGERETQ LADLWRELLG VEQVGRHDNF FALGGHSLLG
VRLISRIRSA LGLELPLATL FAQPRLAELA QALDNAATSK LPSIVTTDRS APLPLSFAQQ
RLWFLNQLDP RTGTTYLMHG GVRLSGMLHV PALRRALDRI VARHDALRTR FSSVDDVPCQ
IVAAPFALDL HLIDLSKKPD AEAAARAHAH AEVSTGFDIA NGPLIRGRLL RLAEHEHVLL
LSMHHIISDG WSIGVLIEEL GILYTAFVSD ALDPLPPLPI QYADYAAWQR RWVDGEQQQR
QLEYWCAQLR NAPAVLELPT DRPRPPVQDT AGDDVELVLD EALSMRVHAL ALEQGTTSFA
LLLSAWAVLL TRYSGQTDLV IGTPSAGRHR SELEPLIGFF VNTLPLRIDL SARPSFVALL
EQVQSNLLAA QANENIPYER IIEAVRPVRS LAHAPLCQAM FSSDTTPSRA LDLPELQLRA
YPNDHRVAQF DLSLDMQIAP SRIGGMLRYA TALFDRSTMQ GYLAHYARLL AALVDAPTLA
VDRHPLLDAT QWHLLQQWNR TTSPLQAPTT LHSAFQAQAR RTPDAVAVID GTQHLCYAEL
DAYSDRIAQQ LVQAGVSPGA CVATLLPRSA ALVAAQLGIL KAGAAYVPLD PQQPAARHAQ
LADVCQARAI VHAPSEAPPW ANAPCLPIVL DTMAALPFAA PPLPACAPAY VMYTSGSSGT
PKGVMVPHQG VLNLVRDPDY ASWQANDRFA FASNPAFDSS TLEVWAPLLS GGSVVVVPQE
VMLDPSALAD FARHHAITVL ILVAGVLRAY ASELARELPT LRYLITGGDI ADPQALATLL
RDTPPQTLLQ TYGPTETTQF VTALALTDVA DDGRRIPIGK PIGNLRVHVL DRHRQALPVG
MQGELHIAGL GLALGYLRQP GLTAEHFVPD PFSEEPGARM YRTGDLGRWR ADGLLECLGR
GDAQSKIRGF RLEPGEIEAA LQRHPEVSQA LVRVREDVPG QRRLVAYVIG THADATSTPD
PSALRRHLAA TLPEYMLPDA YVGMQAWPLT PNGKVDVRAL AIPDDAQRGI AEVEPPQGES
ECALAQIWCE LLGVGNVNRH DNFFDIGGHS LLAVQLTTRI QARLGRRLPL SRLFAEPTLA
RMAAAMADSN VASSAPIAAL VDRSRYYE
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