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Database: UniProt
Entry: D2UXU1_NAEGR
LinkDB: D2UXU1_NAEGR
Original site: D2UXU1_NAEGR 
ID   D2UXU1_NAEGR            Unreviewed;      1733 AA.
AC   D2UXU1;
DT   02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   02-MAR-2010, sequence version 1.
DT   11-JUN-2014, entry version 30.
DE   SubName: Full=Predicted protein;
GN   ORFNames=NAEGRDRAFT_61241;
OS   Naegleria gruberi (Amoeba).
OC   Eukaryota; Heterolobosea; Schizopyrenida; Vahlkampfiidae; Naegleria.
OX   NCBI_TaxID=5762;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NEG-M;
RX   PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA   Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B.,
RA   Carpenter M.L., Field M.C., Kuo A., Paredez A., Chapman J., Pham J.,
RA   Shu S., Neupane R., Cipriano M., Mancuso J., Tu H., Salamov A.,
RA   Lindquist E., Shapiro H., Lucas S., Grigoriev I.V., Cande W.Z.,
RA   Fulton C., Rokhsar D.S., Dawson S.C.;
RT   "The genome of Naegleria gruberi illuminates early eukaryotic
RT   versatility.";
RL   Cell 140:631-642(2010).
CC   -!- SUBCELLULAR LOCATION: Nucleus (By similarity).
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DR   EMBL; GG738845; EFC50347.1; -; Genomic_DNA.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.60; -; 2.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR009057; Homeodomain-like.
DR   InterPro; IPR017877; Myb-like_dom.
DR   InterPro; IPR001005; SANT/Myb.
DR   InterPro; IPR007309; TFIIIC_Bblock-bd.
DR   Pfam; PF04182; B-block_TFIIIC; 1.
DR   Pfam; PF00046; Homeobox; 1.
DR   Pfam; PF00249; Myb_DNA-binding; 1.
DR   SMART; SM00389; HOX; 1.
DR   SMART; SM00717; SANT; 1.
DR   SUPFAM; SSF46689; SSF46689; 2.
DR   PROSITE; PS50090; MYB_LIKE; 1.
PE   3: Inferred from homology;
KW   Complete proteome; DNA-binding; Homeobox; Nucleus.
SQ   SEQUENCE   1733 AA;  200679 MW;  7E33899D4A2DAA7E CRC64;
     MDKVLEASTL EIALEGFRGC SFEKLVKLLQ EYHEYDIKED EDMQICLWSY LLRNSKLSFF
     KIVPNNGDSS TTNNTPPPKQ KSNKKAPQKN DYQYTTEGFQ EYAETRNNFD SRFSSKRLLV
     DNLSELGTLP TSDICIVAQF EYRKFALGLD IRSDVEISEI QYCMLEEVGR SRYSGRFQND
     LTKYLCIDSR STLYHLKRLY GLNLLLKKSS YDPRSKTTSN LIHLFRFTDT KKQKEFIKKT
     DDEVNAEKIF ERYSQLKENI VDTVVGMLTK AKGNVLIDYE VRKKLLDFVK DDTQQKHKWE
     RLKLILQASG KVEYFKAIFE NRLTYCVRLL NQDNNLSSSN PIATNNAIED GLLNPGFDME
     RPQLYQMYDY IEKFGGKSGL NHMDIYQHFE MTSKVSGNLC NDLRKDFGVT SVAEKGEKQA
     KSTSYRFFVP YIKEVENDKA NEVSNNEQES PQKSKSRKKK KSQPPKQSTN NSQEQVQQEV
     QSVLPSINLE DSSDSLYDSD TGSDDESDEN KPALTPSQYL RTEGKRKEEG SRKEVITKNF
     SERCKLALSF LKEKKCIARF QLREHFKQNN VSVESKAISR LIQYLESNNL AKKMTIAVPS
     LFGTTSKMHI CLIDCSLDMK SKTVQDFITS LYSHEVQVNS KEKVDRTILE KVDSIDHLET
     KRSQKRFSYL PLFHSLLNGY INAKMLRVRV FHQYLWNKVN EGSVNPERIC LYDIYSNMSV
     SLFCKLVGCI AEIRLGSDDK EILQTVTISN APENIKKAVD ASVVGRRAVA LSRVETFIDI
     MEKLGLLVVQ AIRDKESKSK VFSLLKTVEF PFPQQFPATE YRQVTFNSIN DVEEYWDDLE
     MCSVNMETIR CEPIGDDQED SPQIFSKIQD LGKRPSWTEY RHFSLRQLRI LEASYKENQT
     PNFEECDNIC KKLRIPMEQV VLYFYRYRNS ILSKRISDIG TIPEGQSKSN TKRKKDDDFI
     VGDDEIEYES NDENVEVRAK KTKRLPSVSL LLIGNRKTRK GSTRKGNKKQ PTDTNENTEK
     QKEKTIPTRG YKWTNEQDLL LLEGLSRLRE LDPSTGTFLT KPIKWQEIAD SIGDGITANR
     CKLRWNNVLR KLPWCKRALE LAIGHRDLNK NNPNIPPIEI RTLVQTCRDQ YRIGPSDSNN
     QLMSVDLPRD LINIVKYFKV IRFEPLVEDN ADENINITTE NRLRLSSLET LFKIILLTPD
     EHYDVKLANK LVKRFKSKEI EECFNSLRKR SIISKSKRGL RMKGYHLNIN FTTKTTVNFY
     PPEIFEDAPK FRKRALMINE EDDSDEEDDM EVKPLFNRHG ACFNPQSSGG VVAALMSMVM
     LEEIRLIPRV APLSEEEKNQ VGRTRSIQDM EEDDGTGVSN HLLRVGAVRP GENDHIHAEG
     TNIKSSHGSL QLPDWTIAIE SITEVNLFSE MGAENEHQTH ISRIVSEYGH KLSSIEFSIE
     LPDQENENKR ERDEFNQDNT YDPPQKKKKQ HHITNSEIEA YFEMYAAESS SITTFTNDQI
     DFVENITYPE IKPLAQYIIE SGVEEYSFWI ERIILVYSFI GNTKFEGANF DTISQKFSDF
     STDYDLSIKE ILQQLVNFNC IVEVNSENET RFLRFEEAKL HTIPYSENGA TQYRPISVFR
     QLSGELNDNL LQNFKKCIIS RIMRYPGILE KKLINSIGVI SAQDIRKVLG FLEDDQIIQS
     SYHRATSNEK LKCKNILFMH QDEMDDLENS DCYPTEFHRS LFVTPKYIFF STQ
//
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