ID D2V1F0_NAEGR Unreviewed; 1284 AA.
AC D2V1F0;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC49155.1};
GN ORFNames=NAEGRDRAFT_45871 {ECO:0000313|EMBL:EFC49155.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC49155.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC49155.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
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DR EMBL; GG738848; EFC49155.1; -; Genomic_DNA.
DR RefSeq; XP_002681899.1; XM_002681853.1.
DR STRING; 5762.D2V1F0; -.
DR EnsemblProtists; EFC49155; EFC49155; NAEGRDRAFT_45871.
DR GeneID; 8855157; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_45871; -.
DR eggNOG; KOG2715; Eukaryota.
DR InParanoid; D2V1F0; -.
DR OrthoDB; 2912088at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0009882; F:blue light photoreceptor activity; IEA:InterPro.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR Gene3D; 3.30.530.20; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR036046; Acylphosphatase-like_dom_sf.
DR InterPro; IPR045068; BACURD1-3.
DR InterPro; IPR007024; BLUF_domain.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR023393; START-like_dom_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR PANTHER; PTHR11145:SF8; BTB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11145; BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN FAMILY MEMBER; 1.
DR Pfam; PF04940; BLUF; 1.
DR Pfam; PF02214; BTB_2; 2.
DR SMART; SM01034; BLUF; 1.
DR SUPFAM; SSF54975; Acylphosphatase/BLUF domain-like; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
DR SUPFAM; SSF54695; POZ domain; 2.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50925; BLUF; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000006671}.
FT DOMAIN 651..747
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 1131..1226
FT /note="BLUF"
FT /evidence="ECO:0000259|PROSITE:PS50925"
FT REGION 940..961
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 37..97
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 261..311
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1284 AA; 149901 MW; A303AF43A00E33DE CRC64;
MPRTNPGAQK KRSNSAIDLT EEDEVVQISD EEEEVIKKRN ERLLQKQREA MIRYERAQSE
TSFNEEFTQI ASELYTLTKH NESMETLITQ IDRLNIKDPM EETEKSKIDL LAEQIIKQSD
DIVSFNVSGQ VFTTTKGTIR REKESFLTVL IDENSHLPFD TDESGAFIIE RSALLFSYIL
KYLQNLDEFT GEFDIDILPK EKTVLNALLE EAKFFSLSNL IEVLDKNNSA QMLEGRSAAR
LVDVWNYGNI VRDAVVSDEY LDQIKERVQR RKEQLNQQRE MIKNLVENQQ KKQVETRRNE
LESKLAQIRQ DLGKVDSLTV FFSISGTIFE MDIFQVFKFK ESLLCKIVQK YNIPIQETKS
RPIFIDREPE QFTHIKYFIE NECLSEDLLY GRSYNKKALL KEAAFYNITD LVKYLDPVYR
FPIEELGSHN VVMKREEDLL RSYFATNRDH PLLSDPYLHL INVFDNLDTF KKQPFPDRGN
ILFKQYSDHL FVESREEFEF NFNCFTKGIF NVKADFTNSR GLARLLLLEK KSTYILGEKD
QRVTENTIIK FTAEERQKLL FNNWDMDSDY LGVLIAFKYR GVPTFFSDLL EMLQSGLTQT
KLIMTVDEIE TILNIPDQKL AQCELTKRIE WIKIDPDSSC NIMNESATNY EDYQFSFEKL
YREKETRLLM KEYMEMEMEV NIGRKEKEVV MLKYKQLQSQ WSESSSAILE PVKIWEIFEE
ARIVIMTELK QDVFPRFIRS QRFISFIQTH DKEFLDKIGL NLGRRISDTV SVSSDESSGN
STTQRKKVTV DYSVRPEFYW KNYQADASIH NITQQDVKFV NSLTLDSNIW QLFKVGDKKK
GEYFASFVSK QKLSVFKPDS TTERQVNPQK LYKFTGVINH SLEELLFTLT NPAYMMDYDN
QLSVVEQLDY LNGFDYSSSI SVQGSSSAFW ENENFDDSSS DGGLSVDSQS STSPKVSHSD
DKFSSSICLE TYPFGWPISN RDFLVTQSLI YEAKTQRYIL VKKSISHPNY PKRKGTTRGF
IVGGWTIQRV TENQTRFCFV SFTDMDLNER VFNQLCKKKG KRLFDGLNQT LDRNSENGFL
RPLFSCGLLE TLEDFLKFYK LPETILNETQ VQVLKKQKSD KFKSFEIDGS LVRLIYVSRY
DESKLSSKDF DQINQVSNRN NQPLNLSGIL LSGQGVFYQV LEGDPKFIYP TYERIKKDSR
HFDVWCVSEE SGVKECERQF SNWAMKCVDL VNSDHYLAQF MRNIIETLSK LSKASRDSTN
WDEENHALDV LYQASKQLND SSKN
//
