ID D2V317_NAEGR Unreviewed; 236 AA.
AC D2V317;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC48552.1};
GN ORFNames=NAEGRDRAFT_63194 {ECO:0000313|EMBL:EFC48552.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC48552.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC48552.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
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DR EMBL; GG738850; EFC48552.1; -; Genomic_DNA.
DR RefSeq; XP_002681296.1; XM_002681250.1.
DR AlphaFoldDB; D2V317; -.
DR EnsemblProtists; EFC48552; EFC48552; NAEGRDRAFT_63194.
DR GeneID; 8862316; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_63194; -.
DR eggNOG; ENOG502QTDK; Eukaryota.
DR InParanoid; D2V317; -.
DR OMA; TQHHWQH; -.
DR OrthoDB; 36492at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0051213; F:dioxygenase activity; IEA:InterPro.
DR GO; GO:0006307; P:DNA dealkylation involved in DNA repair; IEA:InterPro.
DR GO; GO:0035552; P:oxidative single-stranded DNA demethylation; IEA:InterPro.
DR Gene3D; 2.60.120.590; Alpha-ketoglutarate-dependent dioxygenase AlkB-like; 1.
DR InterPro; IPR027450; AlkB-like.
DR InterPro; IPR037151; AlkB-like_sf.
DR InterPro; IPR032854; ALKBH3.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR PANTHER; PTHR31212; ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3; 1.
DR PANTHER; PTHR31212:SF4; ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3; 1.
DR Pfam; PF13532; 2OG-FeII_Oxy_2; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006671}.
FT DOMAIN 132..235
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
SQ SEQUENCE 236 AA; 27398 MW; C891B126C7D60CE4 CRC64;
MVDETREKNQ STVMNSNVVL NIPINLVIHP LVSKPSYIIK EASIGVQVQY FERFLHAHFA
SILFKKFNES MDLFTKDQLV IHGKHIEAPR KTLSYSDSNI VYSYSGMQRS SIPWFPELLK
LKTLIQEKTG EVFNYALVNV YDNGNDYIGW HSDKTKDLVE NSSIVSLTLG ETRPFQFKPS
EGKQKNSDKS IITKYLPNGS MIIMNWNTQF YYKHCLPKRK NISKQRINIT FRHVKV
//
