ID D2V9U5_NAEGR Unreviewed; 368 AA.
AC D2V9U5;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC46201.1};
GN ORFNames=NAEGRDRAFT_65632 {ECO:0000313|EMBL:EFC46201.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC46201.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC46201.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
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DR EMBL; GG738859; EFC46201.1; -; Genomic_DNA.
DR RefSeq; XP_002678945.1; XM_002678899.1.
DR AlphaFoldDB; D2V9U5; -.
DR EnsemblProtists; EFC46201; EFC46201; NAEGRDRAFT_65632.
DR GeneID; 8850573; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_65632; -.
DR eggNOG; ENOG502S2XU; Eukaryota.
DR InParanoid; D2V9U5; -.
DR OMA; FIMQFVN; -.
DR OrthoDB; 6541at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.144.10; Phosphatidic acid phosphatase type 2/haloperoxidase; 1.
DR InterPro; IPR036938; P_Acid_Pase_2/haloperoxi_sf.
DR InterPro; IPR000326; P_Acid_Pase_2/haloperoxidase.
DR PANTHER; PTHR14969:SF58; PAP2 SUPERFAMILY PROTEIN; 1.
DR PANTHER; PTHR14969; SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE; 1.
DR Pfam; PF01569; PAP2; 1.
DR SUPFAM; SSF48317; Acid phosphatase/Vanadium-dependent haloperoxidase; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006671};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..368
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003037386"
FT TRANSMEM 73..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 123..229
FT /note="Phosphatidic acid phosphatase type 2/haloperoxidase"
FT /evidence="ECO:0000259|Pfam:PF01569"
SQ SEQUENCE 368 AA; 41885 MW; F232A5294C1C9307 CRC64;
MMKQLSLLFV LFLTLSSVMM MVSADSTTTT LGEKSYCINE LDDSFINKCH RQVPTNFLTM
VANFVVQWVN PRTLAITAVI FLLAIPVLQI ASVRRDSQII RHTLAKFLHN KIVILNFLHR
VCYTLVLDVA LYTVFRQIRP CSCTTDGGNT FQHFGSRYGM PSGDAMSGAI FGIFLFDVAP
YHGWLARAFA IIIIPIVCLE RVVLGYHTVA QVTVGSCMGI ALHYYSTRAP QFMIFFDGIV
QIVLGAILLQ VDPSLVNERD SMNNLFSWYV WGVSFQIYVF MEIGRYYFKK KNFKKIRYSL
QHLISTKQIG EEVDSDIDHE KDTKHLDAQM DVTKLTDFGF TCISFTLMSI INFFSTAIGQ
EGWLTKMH
//
