ID D2VAD4_NAEGR Unreviewed; 349 AA.
AC D2VAD4;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC46287.1};
GN ORFNames=NAEGRDRAFT_32349 {ECO:0000313|EMBL:EFC46287.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC46287.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC46287.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG738859; EFC46287.1; -; Genomic_DNA.
DR RefSeq; XP_002679031.1; XM_002678985.1.
DR AlphaFoldDB; D2VAD4; -.
DR STRING; 5762.D2VAD4; -.
DR EnsemblProtists; EFC46287; EFC46287; NAEGRDRAFT_32349.
DR GeneID; 8859528; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_32349; -.
DR eggNOG; KOG1575; Eukaryota.
DR InParanoid; D2VAD4; -.
DR OMA; HRPDYNT; -.
DR OrthoDB; 5357470at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR CDD; cd19079; AKR_EcYajO-like; 1.
DR Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR InterPro; IPR023210; NADP_OxRdtase_dom.
DR InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR PANTHER; PTHR43364:SF4; NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN; 1.
DR PANTHER; PTHR43364; NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED; 1.
DR Pfam; PF00248; Aldo_ket_red; 1.
DR SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006671}.
FT DOMAIN 16..338
FT /note="NADP-dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00248"
SQ SEQUENCE 349 AA; 39653 MW; 5BA7EE8C60228BF9 CRC64;
MKYVKFGNTG LKVSQICFGC MSFGSPKWQP WVLDEAQSLP ILKKAWDLGI NFFDTADMYS
NGESERILGK FIKENNIKRE EIVIATKVFF PIDKSGEQKT LFRNGVQNLV PNTYGLSRKH
IMHAVEDSLQ RLGTDYIDLY IIHRWDNNTP IEETMEALHD LVKSGKVRHI GASSMWAWQF
AKAQHVAEMK GWTKFVSMQN LYNLLYREEE RDMIPLCKDQ LTTCTPWSPI SRGILARAHE
FADSTQIEGS STRATTDPFA KQFEKELTEG DKETLRRVSE IAKKKDVTPA QIAIAWLLTK
PYVSAPVVGV TKIENVELNV AATEIVFTEE EIKHLEGAYV TKAVQGALQ
//
