ID D2VHD5_NAEGR Unreviewed; 745 AA.
AC D2VHD5;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC43782.1};
GN ORFNames=NAEGRDRAFT_79940 {ECO:0000313|EMBL:EFC43782.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC43782.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC43782.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
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DR EMBL; GG738871; EFC43782.1; -; Genomic_DNA.
DR RefSeq; XP_002676526.1; XM_002676480.1.
DR AlphaFoldDB; D2VHD5; -.
DR STRING; 5762.D2VHD5; -.
DR EnsemblProtists; EFC43782; EFC43782; NAEGRDRAFT_79940.
DR GeneID; 8856594; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_79940; -.
DR eggNOG; KOG0274; Eukaryota.
DR InParanoid; D2VHD5; -.
DR OrthoDB; 721380at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19846:SF0; SFM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR19846; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS00678; WD_REPEATS_1; 3.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000006671};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 420..460
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 493..516
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 521..561
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 562..601
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 714..745
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 52..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 255..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 163..228
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 745 AA; 83924 MW; 11F418DC7207B611 CRC64;
MYQNGSNQPS PTTNNNNMGF RQPRNMNNTS SNSNNQYIGD IPYGMTEQMM MMQQQQQQNN
QLPPSQQQHY SPRSPSSPIL YVHHSQQVQS PPPQQQLYNN MAMQQGSFMG SGGGIVYNQP
HPSQQQTNNY IDDGNLSATG SVGSMRMAPS IGIRPSSNTS SYYAELQMES QALSQQFEKL
KDQRNQVRNE LGHLEELIFK YQERKSMMED KERRLDKLQQ TIRQKLKGVQ EKIFKLDEKT
NKGEEIKYKA QFNGKINNNN GRGDETNNNQ GSSPATIPEE EITNNLTNNN QILESITISD
VQSEDDNESQ NLDDIINEDI DDDAWISLPA NIYHQMSNNN RTQISHNVYR PQLSTRNKHR
AFQHHTLDDV VFSTQFRTRS ASFNFQQSTS GQMTPRTYRK KVLKELADSD TPFDLSECTL
RGHTKSITSL HMIGSRFVIS GSADCSVRVW DLQSKKCLQT LFGHSGWVRS VTSDFVDVTE
GEEYERLIDD LKFVVSGSGD GTIRLWDVSN PDLEEKCLRI LKGHEGGVTC VKSDINGVII
SGSVDKTVKV WDKNQSECVQ TLIGHERYVK TLQFKSQFLV TGGGDKCMRL WDLRSGKCNK
RINTHDAINV LQFTDDRIIV GCQSGQILDY DLKAGKLLDS LASHGGPISG LKFLGSRLIF
SSTVPITSAF KNGTNETAAY SSTRNSTSKM NGRSFLCLNP IEYNLETKKT TREFFGHIGS
VNSLDFSSTK LVTGSTDHTI KSWTL
//
