GenomeNet

Database: UniProt
Entry: D2VHQ3_NAEGR
LinkDB: D2VHQ3_NAEGR
Original site: D2VHQ3_NAEGR 
ID   D2VHQ3_NAEGR            Unreviewed;       477 AA.
AC   D2VHQ3;
DT   02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   02-MAR-2010, sequence version 1.
DT   28-MAR-2018, entry version 44.
DE   SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC43633.1};
GN   ORFNames=NAEGRDRAFT_34178 {ECO:0000313|EMBL:EFC43633.1};
OS   Naegleria gruberi (Amoeba).
OC   Eukaryota; Heterolobosea; Schizopyrenida; Vahlkampfiidae; Naegleria.
OX   NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN   [1] {ECO:0000313|EMBL:EFC43633.1, ECO:0000313|Proteomes:UP000006671}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NEG-M {ECO:0000313|EMBL:EFC43633.1,
RC   ECO:0000313|Proteomes:UP000006671};
RX   PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA   Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B.,
RA   Carpenter M.L., Field M.C., Kuo A., Paredez A., Chapman J., Pham J.,
RA   Shu S., Neupane R., Cipriano M., Mancuso J., Tu H., Salamov A.,
RA   Lindquist E., Shapiro H., Lucas S., Grigoriev I.V., Cande W.Z.,
RA   Fulton C., Rokhsar D.S., Dawson S.C.;
RT   "The genome of Naegleria gruberi illuminates early eukaryotic
RT   versatility.";
RL   Cell 140:631-642(2010).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; GG738872; EFC43633.1; -; Genomic_DNA.
DR   ProteinModelPortal; D2VHQ3; -.
DR   STRING; 5762.XP_002676377.1; -.
DR   EnsemblProtists; EFC43633; EFC43633; NAEGRDRAFT_34178.
DR   eggNOG; KOG0471; Eukaryota.
DR   eggNOG; COG0366; LUCA.
DR   InParanoid; D2VHQ3; -.
DR   OMA; NFIRRIR; -.
DR   Proteomes; UP000006671; Unassembled WGS sequence.
DR   GO; GO:0004556; F:alpha-amylase activity; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.40.1180; -; 1.
DR   InterPro; IPR013777; A-amylase-like.
DR   InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   Pfam; PF00128; Alpha-amylase; 1.
DR   PIRSF; PIRSF001024; Alph-amyl_fung; 1.
DR   SMART; SM00642; Aamy; 1.
DR   SUPFAM; SSF51445; SSF51445; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000006671};
KW   Disulfide bond {ECO:0000256|PIRSR:PIRSR001024-4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006671}.
FT   DOMAIN       37    384       Aamy. {ECO:0000259|SMART:SM00642}.
FT   ACT_SITE    216    216       Nucleophile. {ECO:0000256|PIRSR:
FT                                PIRSR001024-1}.
FT   ACT_SITE    246    246       Proton donor. {ECO:0000256|PIRSR:
FT                                PIRSR001024-1}.
FT   SITE        312    312       Transition state stabilizer.
FT                                {ECO:0000256|PIRSR:PIRSR001024-2}.
FT   DISULFID     54     61       {ECO:0000256|PIRSR:PIRSR001024-4}.
FT   DISULFID    163    177       {ECO:0000256|PIRSR:PIRSR001024-4}.
SQ   SEQUENCE   477 AA;  54415 MW;  AFAC1DAF9C80EB7C CRC64;
     MLPIHHHHHQ NSNPIKKGKV NNIGKSSAEW RSRSIYQIIT DRFSPSESGS GKSCPLLYTY
     CGGTFQGITS HLNYVKSLGF NAIWISPIVL NLPGGYHGYW AQDWFAVNPH FGTQADLINL
     VKTAHSMDIW VMVDVVFNHV GPVGFDFSEI SPFNSSTHYH PYCQINNWSN QTEVEYCRLA
     DLPDLDQSNN FVYKTLSNWI TDFVLNTFGF DGIRIDTVPE ISKTFWSDLK TNILAPKYGD
     IYSIGEVLNG DMNYVAPYAN ILGATLHYPM YFVLKSIFSQ GGSMYQIRNT INSARSLVKD
     TSLLGVFIDN HDNPRFLNYE SDYKLYQNAL TYVLTSEGIP IFYYGTEQGF NGGADPFNRE
     PLWPTSFNQN SYLFTFVQKI MNFRNTHFQE FLNNPLQVER YVANNFYAFS RGNVFVATTN
     VGSSYGRLQY TITYHPYSDG TVLCDIFWGN NDCETVTNGQ FTVVLLNGES KIYYPQQ
//
DBGET integrated database retrieval system