ID D2VWP1_NAEGR Unreviewed; 536 AA.
AC D2VWP1;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC38730.1};
GN ORFNames=NAEGRDRAFT_73452 {ECO:0000313|EMBL:EFC38730.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC38730.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC38730.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG738905; EFC38730.1; -; Genomic_DNA.
DR RefSeq; XP_002671474.1; XM_002671428.1.
DR AlphaFoldDB; D2VWP1; -.
DR EnsemblProtists; EFC38730; EFC38730; NAEGRDRAFT_73452.
DR GeneID; 8858103; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_73452; -.
DR InParanoid; D2VWP1; -.
DR OrthoDB; 5397676at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.120.550; Membrane associated eicosanoid/glutathione metabolism-like domain; 1.
DR InterPro; IPR023352; MAPEG-like_dom_sf.
DR InterPro; IPR001129; Membr-assoc_MAPEG.
DR PANTHER; PTHR31004; TRANSMEMBRANE PROTEIN 79; 1.
DR PANTHER; PTHR31004:SF1; TRANSMEMBRANE PROTEIN 79; 1.
DR Pfam; PF01124; MAPEG; 1.
DR SUPFAM; SSF161084; MAPEG domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006671};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 342..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 465..486
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 493..512
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 518..535
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 63..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 110..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 162..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 194..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..30
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..48
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 536 AA; 61625 MW; B2A97C453FAA5343 CRC64;
MSQHQQLTEN SSSSSPTSKP SSSTTQQEDD DQMVKAPHVS EDDHHAVNNQ VIMQEEQEPH
IVEPITSSST NNHHTQPIYS INDGEEIGEK KEINTDMDIT TQQQYNKQSL VSGGVGNDQT
PESSSEGILI KPSHGSFLSF EQLVEEEANA LLYDDNTLEE MESDNVNNNE EKKSPQTPNS
SLVNMMDFST ILSNSEKLLS TRKDDEEEEE EEEEEPISTK PIPLQSKIIH TKSEGNLDTF
ITRRNRTETY PSTPTLLKQR IMQKYKQQIQ QQSSFATDTD TDDDMLLTSM SQNRYFRLFS
LMIAKFFRIQ SRVIAPNGSS PQSIEAIRKQ EKANRTIQRD MLTMFISGFS MFGIFAIIWY
NIYFNTDVLK NILEGRDNLT ERFYFTMKCI FVSSWIFPLV FVAIVRNRLF EEASNPLLTN
LINKEHQLRI TIHQRVLQNS IEQFIMHSMG CLILGYYVSR ENLRIIVFAS ITFLLCRIFF
WIGYTIHHSL RTLGMLTNAC TTIAMLCFST YYITTQDILP FIINDIILPI FVIFSA
//
