ID D2VZQ0_NAEGR Unreviewed; 348 AA.
AC D2VZQ0;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=VWFA domain-containing protein {ECO:0000313|EMBL:EFC37699.1};
GN ORFNames=NAEGRDRAFT_74571 {ECO:0000313|EMBL:EFC37699.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC37699.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC37699.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
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DR EMBL; GG738915; EFC37699.1; -; Genomic_DNA.
DR RefSeq; XP_002670443.1; XM_002670397.1.
DR AlphaFoldDB; D2VZQ0; -.
DR STRING; 5762.D2VZQ0; -.
DR EnsemblProtists; EFC37699; EFC37699; NAEGRDRAFT_74571.
DR GeneID; 8857616; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_74571; -.
DR eggNOG; ENOG502S39S; Eukaryota.
DR InParanoid; D2VZQ0; -.
DR OrthoDB; 22122at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR47824; UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR47824:SF3; UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006671}.
FT DOMAIN 37..242
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 348 AA; 38808 MW; 394FBB9EE8A29850 CRC64;
MSFNITSLAK GKWIRANHLE EPGYDQELVD WSEKLVDLVI VMDNTSSMSG EIKIAKDTVQ
SIITTLHDHF QSDLRFSAVS YRDHTDDYVV KEYPFTKNVE KAKGYVNEMF AKGGGDMPEA
LASALKVVNE IPFNKKGRKI CIWIADAPPH GMGASGDYFP DGCKDEQGEI IDWIKLASHL
QEKNVVFYSI ICGRSKNDQQ LSLFMDYLAT KTDGKCMLLT EANKIPNLII NGCIEDEQMD
RLVEERIKEL GKENAKAMKE EELIAHVHKL TLEAKVPQVH NYKVSSSRTG ALLACSSMSS
VDRNWYSTAT NAFQAEGASD NPFSVGSVSV APPTTDQLKK ACARNLRK
//
