ID D2W0G4_NAEGR Unreviewed; 179 AA.
AC D2W0G4;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC37473.1};
GN ORFNames=NAEGRDRAFT_74848 {ECO:0000313|EMBL:EFC37473.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC37473.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC37473.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
CC -!- SIMILARITY: Belongs to the G-alpha family.
CC {ECO:0000256|ARBA:ARBA00005804}.
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DR EMBL; GG738918; EFC37473.1; -; Genomic_DNA.
DR RefSeq; XP_002670217.1; XM_002670171.1.
DR AlphaFoldDB; D2W0G4; -.
DR STRING; 5762.D2W0G4; -.
DR EnsemblProtists; EFC37473; EFC37473; NAEGRDRAFT_74848.
DR GeneID; 8861076; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_74848; -.
DR eggNOG; KOG0082; Eukaryota.
DR InParanoid; D2W0G4; -.
DR OMA; YICATRS; -.
DR OrthoDB; 5471456at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0019001; F:guanyl nucleotide binding; IEA:InterPro.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF302; GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-8 SUBUNIT-RELATED; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006671}.
SQ SEQUENCE 179 AA; 20781 MW; 64CE56DC0AC164FB CRC64;
MGGSRHERKK WIHQFNSADV ILFVVSLSEF DTNCFEDGET PRWKESFDIF MNLLYNPSFA
KLPFVLLFNK KDVLEQKLVN QSFASHFDDF PSDKNGQNID DCIQFIVDKY SSSVKTRQLL
LNPGECCVDP NDENAGPSML VRVLNAFDEN NLLTVFKDIT EYSIREHQRR YLQALVQSK
//
