ID   D2W3N9_NAEGR            Unreviewed;       566 AA.
AC   D2W3N9;
DT   02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   02-MAR-2010, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC36294.1};
GN   ORFNames=NAEGRDRAFT_76012 {ECO:0000313|EMBL:EFC36294.1};
OS   Naegleria gruberi (Amoeba).
OC   Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC   Vahlkampfiidae; Naegleria.
OX   NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN   [1] {ECO:0000313|EMBL:EFC36294.1, ECO:0000313|Proteomes:UP000006671}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NEG-M {ECO:0000313|EMBL:EFC36294.1,
RC   ECO:0000313|Proteomes:UP000006671};
RX   PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA   Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA   Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA   Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA   Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT   "The genome of Naegleria gruberi illuminates early eukaryotic
RT   versatility.";
RL   Cell 140:631-642(2010).
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DR   EMBL; GG738933; EFC36294.1; -; Genomic_DNA.
DR   RefSeq; XP_002669038.1; XM_002668992.1.
DR   AlphaFoldDB; D2W3N9; -.
DR   EnsemblProtists; EFC36294; EFC36294; NAEGRDRAFT_76012.
DR   GeneID; 8862062; -.
DR   VEuPathDB; AmoebaDB:NAEGRDRAFT_76012; -.
DR   InParanoid; D2W3N9; -.
DR   OrthoDB; 5515111at2759; -.
DR   Proteomes; UP000006671; Unassembled WGS sequence.
DR   InterPro; IPR025197; DUF4116.
DR   Pfam; PF13475; DUF4116; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000006671}.
FT   DOMAIN          328..373
FT                   /note="DUF4116"
FT                   /evidence="ECO:0000259|Pfam:PF13475"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          524..566
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        530..566
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   566 AA;  67005 MW;  55FEC50E46EF7791 CRC64;
     MKRLNHHQEE VQQDPKRIKF SSSSSTNSIQ AVVITLIDLH SNHLIDENDW CCINYRKLTR
     QMDGLRLWTV RRRQVWDTIS NPKTFHGIPI EHCRDPFTLE KSWAEGLAFN LGTLFQTDNE
     TALEMVKRSP KCFSVLRSKD KDVILEALNT PRIVRYTDLD VIHRYLKSIQ DREYAIQLIT
     KYGKILDFLT HFEEDEEMQL LAFKHGWYIT QLPQKWKELM EDKSNVMEIL QTNKNIIKHI
     PKAMLMDREI LDAIFDSVDS IDDINLIPKE ILNDKEFIFK LLKKGYYFHL IRFGILKNFS
     HDWDFMKTAT SIEPSIFTIC PIDLRSQKEF ALSCLDTVRE SFRFIPEFLQ DDRDILLQAV
     KSDLSVLPRL PQDILQDREK ILTIIRSCEN RSYTTPEFDY FKEDEEIWYE LCVRDHELIH
     QSRFASDTNF LLRVAQKNPR IPISIDFDKL PDLSYFFRES LKVTNSAIFY YLKLYPEFFN
     LEEANEITGL YLSKSSDFNA LFARVLHDKY NNCVLPPQAL KFKPITEESS TDESEEDYDS
     LDSDYAESED EDDELEDEDG EDDEYY
//