ID D2W645_NAEGR Unreviewed; 228 AA.
AC D2W645;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC35457.1};
DE Flags: Fragment;
GN ORFNames=NAEGRDRAFT_76888 {ECO:0000313|EMBL:EFC35457.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC35457.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC35457.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; GG739221; EFC35457.1; -; Genomic_DNA.
DR RefSeq; XP_002668201.1; XM_002668155.1.
DR AlphaFoldDB; D2W645; -.
DR STRING; 5762.D2W645; -.
DR EnsemblProtists; EFC35457; EFC35457; NAEGRDRAFT_76888.
DR GeneID; 8856371; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_76888; -.
DR eggNOG; KOG1225; Eukaryota.
DR InParanoid; D2W645; -.
DR OrthoDB; 101939at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR013111; EGF_extracell.
DR PANTHER; PTHR11219; TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR PANTHER; PTHR11219:SF69; TENEURIN-M; 1.
DR Pfam; PF07974; EGF_2; 1.
DR SMART; SM00181; EGF; 4.
DR PROSITE; PS00022; EGF_1; 2.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Reference proteome {ECO:0000313|Proteomes:UP000006671}.
FT DOMAIN 113..152
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 142..151
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 228
FT /evidence="ECO:0000313|EMBL:EFC35457.1"
SQ SEQUENCE 228 AA; 24284 MW; 6CE13263E24701B4 CRC64;
MANDTSVCSG IGTCVYANNC SCWNSTFWGG QNCDIHKCGN VLANSPSVCS GNGNCLAPGV
CNCTEMYGGS NCNVPKCSNI LATSPEVCSY SKGRCVSPNN CSCSEGYHGS NCELVSCFGV
KNTSLNVCSG KGVCLSLNNC TCQQGFYGEK CQYYDCFSVR NDKKDVCSSH GNCSNIDTCN
CTKPYYGTNC EKFDCYGKAQ DSISVCSSRG FCSSLDNCTC QEGYYGKE
//
