ID   D2WFH4_ECOLX            Unreviewed;       906 AA.
AC   D2WFH4;
DT   02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   02-MAR-2010, sequence version 1.
DT   08-NOV-2023, entry version 20.
DE   SubName: Full=Relaxase/mobilization nuclease {ECO:0000313|EMBL:ADB20491.1};
GN   Name=nikB {ECO:0000313|EMBL:ADB20491.1};
GN   ORFNames=pO26CRL_0082 {ECO:0000313|EMBL:ADB20491.1};
OS   Escherichia coli O26:H-.
OG   Plasmid pO26-CRL {ECO:0000313|EMBL:ADB20491.1}.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=376724 {ECO:0000313|EMBL:ADB20491.1};
RN   [1] {ECO:0000313|EMBL:ADB20491.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=O6877 {ECO:0000313|EMBL:ADB20491.1};
RC   PLASMID=pO26-CRL {ECO:0000313|EMBL:ADB20491.1};
RX   PubMed=19917674; DOI=10.1096/fj.09-144972;
RA   Venturini C., Beatson S.A., Djordjevic S.P., Walker M.J.;
RT   "Multiple antibiotic resistance gene recruitment onto the enterohemorrhagic
RT   Escherichia coli virulence plasmid.";
RL   FASEB J. 24:1160-1166(2010).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GQ259888; ADB20491.1; -; Genomic_DNA.
DR   RefSeq; WP_000991402.1; NC_013728.1.
DR   RefSeq; YP_003377894.1; NC_013728.1.
DR   AlphaFoldDB; D2WFH4; -.
DR   InterPro; IPR005094; Endonuclease_MobA/VirD2.
DR   Pfam; PF03432; Relaxase; 1.
PE   4: Predicted;
KW   Plasmid {ECO:0000313|EMBL:ADB20491.1}.
FT   DOMAIN          62..315
FT                   /note="MobA/VirD2-like nuclease"
FT                   /evidence="ECO:0000259|Pfam:PF03432"
SQ   SEQUENCE   906 AA;  105077 MW;  AF65B469A4D6074B CRC64;
     MNAIIPKKRR DGKSSFEDLI AYTSVRDDVP EDELRPDTEM KAEIPHRNRF RRLVDYATRL
     RNEKFVSLID VMKDGSQWVN FYGVTCFHNC LSLESAAEEM QKAADLAHFS KDDTDPVFHY
     ILSWPAHESP RSEQLFDCVR HTLKSLELSK HQYVAAVHTD TDNLHVHVAV NRVHPETGYI
     NCLPWSQEKL SRACRELEIK HGFAPDNGCF VHAPGNRIVR KTALVRERRN AWRRGKKQTF
     REYIVQMSIA GLREEPAQDW LSLHKRLASD GLYITMQEGE LVVKDGWDRA REGVALSSFG
     PLWTAEKLGR KLGEYQPVPT DIFSQVGTPG RYDPEAINVD IRPEKVAETE SLKQYACRHF
     AERLPEMARN GELESCLDVH RTLATAGLWM GIQHGHLVLH DGFDKQQTPV RADSVWPLMT
     LDYMQDLDGG WQPVPKDIFT QVIPGERFRG RNLGTQAVSD YEWYRMRMGT GPQGAIKREL
     FSDKESLWGY GLIQCRSLIE EMIADGDFSW QACHEMFARK GLMLQKQHHG LVIVDAFNHE
     LTPVKASSIH PDLTLSRAEP QAGPFEIAAA DIFERVKPEC RYNPELAASD EVEPGFRRDP
     EIRRERREAR AAAREDLRAR YLAWKEHWRK PDLRYGERLR EIHAACRRRK AYIRVQFRDP
     QLRKLHYHIA EVQRMQALIR LKESVKEERL SLIAEGKWYP LSYRQWVEQQ AAQGDRAAVS
     QLRGWDYRDR RSRNKDKRRT TNVDRCVVLC EPGGTPLFNN VAKLEARLQK NGSVHFRDTR
     TGKNVCTDYG DRVVFYHHTD RNELAEKLDL IAPVLFSRNG KLGFEPEGSY QQFNDVFAEM
     VAWHNAAGIT GNGHFTITRP DVDLHRQRSE QYYREYIRQQ TRLSVSHDDN YTLRQEKTWE
     PPSPGM
//