ID D2YCT2_VIBMI Unreviewed; 801 AA.
AC D2YCT2;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN Name=nanH {ECO:0000313|EMBL:EEW07443.1};
GN ORFNames=VMB_13290 {ECO:0000313|EMBL:EEW07443.1};
OS Vibrio mimicus VM603.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=671074 {ECO:0000313|EMBL:EEW07443.1, ECO:0000313|Proteomes:UP000004827};
RN [1] {ECO:0000313|EMBL:EEW07443.1, ECO:0000313|Proteomes:UP000004827}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VM603 {ECO:0000313|EMBL:EEW07443.1,
RC ECO:0000313|Proteomes:UP000004827};
RX PubMed=19860885; DOI=10.1186/1471-2148-9-258;
RA Thompson C.C., Vicente A.C., Souza R.C., Vasconcelos A.T., Vesth T.,
RA Alves N.Jr., Ussery D.W., Iida T., Thompson F.L.;
RT "Genomic taxonomy of Vibrios.";
RL BMC Evol. Biol. 9:258-258(2009).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 33 family.
CC {ECO:0000256|ARBA:ARBA00009348}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEW07443.1}.
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DR EMBL; ACYU01000049; EEW07443.1; -; Genomic_DNA.
DR AlphaFoldDB; D2YCT2; -.
DR Proteomes; UP000004827; Unassembled WGS sequence.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR GO; GO:0033691; F:sialic acid binding; IEA:InterPro.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR Gene3D; 2.60.120.200; -; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR InterPro; IPR015344; VCNA_lectin-like_dom.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13088; BNR_2; 1.
DR Pfam; PF09264; Sial-lect-inser; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 2.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 3: Inferred from homology;
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..46
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 47..801
FT /note="exo-alpha-sialidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003039006"
FT DOMAIN 87..239
FT /note="Vibrio cholerae neuraminidase lectin-like"
FT /evidence="ECO:0000259|Pfam:PF09264"
FT DOMAIN 369..565
FT /note="Vibrio cholerae neuraminidase lectin-like"
FT /evidence="ECO:0000259|Pfam:PF09264"
FT DOMAIN 575..768
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13088"
SQ SEQUENCE 801 AA; 87766 MW; 388A9C4CC5758BCC CRC64;
MTSQRRRASI HKETDSNIKG VDMRFKNVKK TALMLAMFGM ATSSNAALFD YNATGDTEFD
SPAKQGWMQD NTNNGSGVLT NADGTPAWLV QGNGGRAQWT YSLSTNQHAQ ASSFGWRMTT
EMKVLSGGMI TNYYANGTQR VLPIVSLDSS GNLVVEFEGQ TGRTILATGT AATEYHKFEL
VFLPGSNPSA SFYFDGKLIR DNIQPTASKQ NMIVWGNGSS NTDGVAAYRD IKFEIQGDVI
FRGPDRIPSI VASSVTPGVV TAFAEKRVGG GDPGALSNTN DIITRTSRDG GITWDAELNL
TEQINVSDEF DFSDPRPIYD PSTNTVLVSY ARWPTDAAQN GDQIKPWMPN GIFYSVYDVA
SGNWQAPIDV TDQVKERSFQ IAGWGGSELY RRNTNLDSQQ DWQSNAKIRI VDGAANQIQV
ADGSRKYVVT LSIDESGSLV ANLNGVSSPI ILQAERAKVH SFHDYELQYS ALNRTTTLFV
DGQQITTWTG EVSQENNIQF GNADAQIDGR LHVQNIALTQ QGQNLVEFDA FYLAQQTPEV
EKDLEKLGWT KIKTGNTMSL YGNASVNPGP GHGITLARQQ NISGSQNGRL IYPAIVLDRF
FLNVMSIYSD DGGSNWQTGS TLPIPFRWKS SSILETLEPS ESDMVELQNG DLLLTARLDF
NQTVNGVNYG PRQQFLSKDG GITWSMLEGN NASVFNNIST GTVDASITRF EQSDGSHFLL
FTNPLGNPAG TNGRQNLGLW FSFDEGLTWK GPIQLVNGAS AYSDIYQLDS ENAIVIVETD
NSNMRILRVP ITLLKQKALS L
//
