ID   D2Z4Q4_9BACT            Unreviewed;       948 AA.
AC   D2Z4Q4;
DT   23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   23-MAR-2010, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=DNA methylase N-4/N-6 domain-containing protein {ECO:0000259|Pfam:PF01555};
GN   ORFNames=Dpep_2376 {ECO:0000313|EMBL:EFC92398.1};
OS   Dethiosulfovibrio peptidovorans DSM 11002.
OC   Bacteria; Synergistota; Synergistia; Synergistales;
OC   Dethiosulfovibrionaceae; Dethiosulfovibrio.
OX   NCBI_TaxID=469381 {ECO:0000313|EMBL:EFC92398.1, ECO:0000313|Proteomes:UP000006427};
RN   [1] {ECO:0000313|EMBL:EFC92398.1, ECO:0000313|Proteomes:UP000006427}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11002 {ECO:0000313|EMBL:EFC92398.1,
RC   ECO:0000313|Proteomes:UP000006427};
RX   PubMed=21304695;
RA   Labutti K., Mayilraj S., Clum A., Lucas S., Glavina Del Rio T., Nolan M.,
RA   Tice H., Cheng J.F., Pitluck S., Liolios K., Ivanova N., Mavromatis K.,
RA   Mikhailova N., Pati A., Goodwin L., Chen A., Palaniappan K., Land M.,
RA   Hauser L., Chang Y.J., Jeffries C.D., Rohde M., Spring S., Goker M.,
RA   Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA   Kyrpides N.C., Klenk H.P., Lapidus A.;
RT   "Permanent draft genome sequence of Dethiosulfovibrio peptidovorans type
RT   strain (SEBR 4207).";
RL   Stand. Genomic Sci. 3:85-92(2010).
CC   -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC       {ECO:0000256|ARBA:ARBA00006594}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFC92398.1}.
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DR   EMBL; ABTR02000001; EFC92398.1; -; Genomic_DNA.
DR   RefSeq; WP_005662435.1; NZ_ABTR02000001.1.
DR   AlphaFoldDB; D2Z4Q4; -.
DR   STRING; 469381.Dpep_2376; -.
DR   REBASE; 62791; M.Dpe11002ORF2376P.
DR   PaxDb; 469381-Dpep_2376; -.
DR   eggNOG; COG0863; Bacteria.
DR   eggNOG; COG1743; Bacteria.
DR   OrthoDB; 9773571at2; -.
DR   Proteomes; UP000006427; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR   InterPro; IPR002941; DNA_methylase_N4/N6.
DR   InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF01555; N6_N4_Mtase; 2.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 2.
DR   PROSITE; PS00092; N6_MTASE; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006427};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          77..182
FT                   /note="DNA methylase N-4/N-6"
FT                   /evidence="ECO:0000259|Pfam:PF01555"
FT   DOMAIN          522..638
FT                   /note="DNA methylase N-4/N-6"
FT                   /evidence="ECO:0000259|Pfam:PF01555"
SQ   SEQUENCE   948 AA;  108583 MW;  910E86E2EBB4E6FA CRC64;
     MNKQKKLFKT KFIPGKLGSG NLFEEELVPA NDGPVKCLGL EFENDDARRA HFTEELRKKL
     QDPEFRKIEG FPIGEDEDIL KLSDPPYYTA CPNPWIGQFI EEWESQKPEK PADYHYHREP
     FAADVSEGKN DPIYNAHSYH TKVPHKAIMR YILHYTEPGD IVFDGFCGTG MTGVAAQMCG
     DRDVVTSLGY QVKPDGTILQ EETDEDGKKV WKRFSKLGAR KAVLNDLSPA ATFIAYNYNT
     PVDVHAFERE AKRILAEVEE ECGWMYETLH TDGKTKGKIN YTVWSDVFVC PECTGEVVFW
     DAAVDKEAGK VRDSFPCPHC HAELTKRKME RAWTTNFDSA LNNSVKQAKQ VPVLINYSIE
     GKRGRFEKSP DKNDLTLIEK IENSEIHYWF PNYRMMKGKE TRRNDPAGIT HVHHFYTKRN
     LCVLAAVRIR SSSSFLISQL AMWWTLTKLY RYRWAGGIAG AGGGPMAGTL YIPSLIKEIS
     VLVSAVDVFN KNIRKKKLFA NFLRHPLSTS SANWIDYNNN SVDYIFTDPP FGANLNYSEL
     SFIWESWLKV WTNNKPEAIE NSVQGKGATE YRNLMAGCFK EAYRVLKPGR WMTVEFSNTK
     ASVWSSIQTA LTEAGFIVAN VSALDKKQGS FKAVTTLTAV KQDLVISAYK PNGGFEDRFE
     EEAKSEEGVW DFIRTHLKYL PVIKKQGYDL VAIPERDPRI LYDQVIAYYV RKGYNVPIDS
     QDFQLGLSQR FAERDGMYFL PEQVAEYDRK KMIGGGRPLQ QSLFISDEAS AIEWLRSLLR
     DKPQSFQDIN PLFMKEIGGW SKNEVGLELS TLLEQNFLAY DGKGPVPDQI HSYLSSNWKD
     MRNLPKEDPA LVAKAKNRWY VPDPNKAGDL EKLREKALLK EFEEYKQAKK KLKIFRLEAV
     RAGFKKAWQE RDYKVIITVA EKIPNNVLEE DPKLLMWYDQ AVTRVGDE
//