ID D3A9L2_9CLOT Unreviewed; 585 AA.
AC D3A9L2;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 24-JAN-2024, entry version 62.
DE SubName: Full=ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein {ECO:0000313|EMBL:EFD01487.1};
GN ORFNames=CLOSTHATH_00283 {ECO:0000313|EMBL:EFD01487.1};
OS Hungatella hathewayi DSM 13479.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Hungatella.
OX NCBI_TaxID=566550 {ECO:0000313|EMBL:EFD01487.1, ECO:0000313|Proteomes:UP000004968};
RN [1] {ECO:0000313|EMBL:EFD01487.1, ECO:0000313|Proteomes:UP000004968}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13479 {ECO:0000313|EMBL:EFD01487.1,
RC ECO:0000313|Proteomes:UP000004968};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFD01487.1}.
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DR EMBL; ACIO01000019; EFD01487.1; -; Genomic_DNA.
DR RefSeq; WP_006770840.1; NZ_GG667608.1.
DR AlphaFoldDB; D3A9L2; -.
DR HOGENOM; CLU_020473_6_1_9; -.
DR Proteomes; UP000004968; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd18773; PDC1_HK_sensor; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR42713; HISTIDINE KINASE-RELATED; 1.
DR PANTHER; PTHR42713:SF2; TWO-COMPONENT SENSOR KINASE YESM; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EFD01487.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 312..363
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
SQ SEQUENCE 585 AA; 65176 MW; 3088DBAB4973598F CRC64;
MGKQFKLRDW SRRFSVQLSL FFLGAGLTVI LLLSGAVYWF ASNLLMSETI SKTHDLLEMS
GANIGTYIAR VKGESNVFAG SPSLRQYLSD DEESLRTGLL SQIDTLLQND SSIKSIVVVS
KDGRILSNEK NLDMSVSSDM MKEDWYIESI HNTMPVLTGA RMQSFSSDKD NWVISVSTEI
TGDSGDNLGV LLMDMEYSVI EDHLRSLDLG REGYVFLLND KGEPVYHKDT SYFSDPDKLA
QLLEIQSAGD GYDKASNLLT CQTQIEKTGW TMVGVVSLDT LKMLERQLFE AVLLTGGLLF
IAVLLIGILF TRRLSTPMAD LERGMNEIEK LAEVRIRKNS FYEVELLAGN YNRMIHRIRI
LMDEISDKEK TLRHAELNAL VSQINPHFLY NTLDTIVWMA EFNDSTRVIA LTKSLAAFFR
LSLSGGRELI TVGDELEHVR QYLYIQKERY GDKLNYTIHA PEEVLDYTVP KIILQPIAEN
SIYHGIKPLD SPGQITITVQ EEGEKLIFTV SDNGAGCRPD AAAADNPSRP GKVGLKNVDE
RLKLYYGPGY GVTIHPAPGA GCRVELTVGK QLFSSPVSSS NSSSA
//
