ID D3AMT5_9CLOT Unreviewed; 366 AA.
AC D3AMT5;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:EFC96875.1};
DE EC=1.3.1.12 {ECO:0000313|EMBL:EFC96875.1};
GN ORFNames=CLOSTHATH_04935 {ECO:0000313|EMBL:EFC96875.1};
OS Hungatella hathewayi DSM 13479.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Hungatella.
OX NCBI_TaxID=566550 {ECO:0000313|EMBL:EFC96875.1, ECO:0000313|Proteomes:UP000004968};
RN [1] {ECO:0000313|EMBL:EFC96875.1, ECO:0000313|Proteomes:UP000004968}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13479 {ECO:0000313|EMBL:EFC96875.1,
RC ECO:0000313|Proteomes:UP000004968};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFC96875.1}.
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DR EMBL; ACIO01000481; EFC96875.1; -; Genomic_DNA.
DR RefSeq; WP_006775365.1; NZ_GG667724.1.
DR AlphaFoldDB; D3AMT5; -.
DR GeneID; 61911244; -.
DR HOGENOM; CLU_055968_2_1_9; -.
DR Proteomes; UP000004968; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EFC96875.1}.
FT DOMAIN 4..291
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 366 AA; 40507 MW; 6B127B912F34E109 CRC64;
MTDSTIAFIG LGLIGGSIAR GIKRENPDTK IMAYMRTRSR LLSAMDEGVI DVILDGADEQ
LSQCDLIFLC TPVEYNARYL AEIKPFLKPG AIITDVGSTK TDIHEEVIRL DMEDCFVGGH
PMAGSEKTGF ENSTDHLLEN AYYIITPTRK SSPAAVERLI SIASLIGSIP IVLDYHEHDS
ITAAISHLPH VIASSLVNLV RDADNQEGLM KRLAAGGFKD ITRIASSSPE MWEQICMTNR
APLAAVLEQY IASLNETLVK LRSGDNQYLS RLFETSRDYR NSISERNQGS VTPEYSFTVD
MADEVGAIST LSVILAAKGI SIKNIGINHN REHGEGTLKI IFYDKEAMDM AWKQLERYHY
DLISNN
//
