ID D3DBM4_9ACTN Unreviewed; 831 AA.
AC D3DBM4;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase {ECO:0000313|EMBL:EFC79685.1};
GN ORFNames=FrEUN1fDRAFT_7196 {ECO:0000313|EMBL:EFC79685.1};
OS Parafrankia sp. EUN1f.
OC Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae;
OC Parafrankia.
OX NCBI_TaxID=102897 {ECO:0000313|EMBL:EFC79685.1, ECO:0000313|Proteomes:UP000004777};
RN [1] {ECO:0000313|EMBL:EFC79685.1, ECO:0000313|Proteomes:UP000004777}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EUN1f {ECO:0000313|EMBL:EFC79685.1,
RC ECO:0000313|Proteomes:UP000004777};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Tice H., Bruce D., Goodwin L.,
RA Pitluck S., Larimer F., Land M.L., Hauser L., Beauchemin N., Sen A.,
RA Fernandez M., Tisa L.;
RT "The draft genome of Frankia sp. EUN1f.";
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFC79685.1}.
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DR EMBL; ADGX01000205; EFC79685.1; -; Genomic_DNA.
DR AlphaFoldDB; D3DBM4; -.
DR Proteomes; UP000004777; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 221..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 321..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 392..532
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 540..831
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT REGION 742..769
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 805..831
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 816..831
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 831 AA; 87481 MW; 464DA68839A72D12 CRC64;
MPMDESGGRV RRPWPAAFGC WACWAFALLT VICVALLPAP YDLQAVDMSC TVATLVATVV
LLSTARRAGA NDRRWRLLVA LTTFGGFLIA LANSWHGIVH GADVYNEIEL VHATFLLAYL
PALAGLLLLP SELVLARAGP RSLPRPHGRH WYVITVLDSA LIVGSGALVA WSTLLAPVVH
RTTLSRPALA IVFSSIAIGL VLVVVAALLA TARRPRSLPT LILLAAGMAV MSVTMGVYLY
LAAATNGVVP AAVHLGYLVS WLLLISAALV PPPPGRPPSE PSPQTGTWVF SVRAVLPYLA
FGAAGAVTLT RLATGTRADE LDFFGLIGLL VFLVCRQLAT IGENARLLSL VDTSRRELHH
QAFHDPLTGV ANRALFAVRL EQAVAAHVRD RRRLAVLYCD VDDFKQINDN LGHSVGDALL
QVVAGRLQSG TRDTDTVARL GGDEFAVVLG GAGGDPEPVA RRLGNIMRAP FRLGEHSYPV
GISLGLVVSE LSPGTGDHGA ATVTADSLLR DADIAMYAAK RAKRGGLVVR RAGRPSSDSP
IHLGGQLAAA LRGEPGSGTL DVVYRDVVDL RDGRVVAFDA GPCWNHPDIG RVDAGRLYRL
ADRGGLARAI DTFLLHRCCE DLGHDTADAG CHGAAAAADR PAVLVPISAA RVAEPSLATE
ILEALAEQRL PPRVIVPAFS AAAAEGGDPV AARNVLGRLR RHGVRCALTE AAGDAATLRL
LRLLPIDIIR LDAALTSVDG EVPANRDAGE AGAGTGAGNQ GRDGEGDPAL ADTIRSALVG
AAIRRGLTVI APAIRGERQE HRLAADGCQL GEGPLYDRER QGRRRHGPAL V
//
