ID D3DH66_HYDTT Unreviewed; 963 AA.
AC D3DH66;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=ATP-dependent dsDNA exonuclease C subunit {ECO:0000313|EMBL:BAI69168.1};
GN Name=sbcC {ECO:0000313|EMBL:BAI69168.1};
GN OrderedLocusNames=HTH_0708 {ECO:0000313|EMBL:BAI69168.1};
OS Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6).
OC Bacteria; Aquificota; Aquificae; Aquificales; Aquificaceae;
OC Hydrogenobacter.
OX NCBI_TaxID=608538 {ECO:0000313|EMBL:BAI69168.1, ECO:0000313|Proteomes:UP000002574};
RN [1] {ECO:0000313|EMBL:BAI69168.1, ECO:0000313|Proteomes:UP000002574}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6534 / IAM 12695 / TK-6 [Tokyo]
RC {ECO:0000313|Proteomes:UP000002574};
RX PubMed=20348262; DOI=10.1128/JB.00158-10;
RA Arai H., Kanbe H., Ishii M., Igarashi Y.;
RT "Complete genome sequence of the thermophilic, obligately
RT chemolithoautotrophic hydrogen-oxidizing bacterium Hydrogenobacter
RT thermophilus TK-6.";
RL J. Bacteriol. 192:2651-2652(2010).
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DR EMBL; AP011112; BAI69168.1; -; Genomic_DNA.
DR RefSeq; WP_012963350.1; NC_017161.1.
DR AlphaFoldDB; D3DH66; -.
DR STRING; 608538.HTH_0708; -.
DR KEGG; hth:HTH_0708; -.
DR PATRIC; fig|608538.5.peg.718; -.
DR eggNOG; COG0419; Bacteria.
DR OrthoDB; 9795626at2; -.
DR Proteomes; UP000002574; Chromosome.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR PANTHER; PTHR32114; ABC TRANSPORTER ABCH.3; 1.
DR PANTHER; PTHR32114:SF2; ABC TRANSPORTER ABCH.3; 1.
DR Pfam; PF13476; AAA_23; 1.
DR Pfam; PF13558; SbcC_Walker_B; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF75712; Rad50 coiled-coil Zn hook; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Exonuclease {ECO:0000313|EMBL:BAI69168.1};
KW Hydrolase {ECO:0000313|EMBL:BAI69168.1};
KW Nuclease {ECO:0000313|EMBL:BAI69168.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002574}.
FT DOMAIN 6..225
FT /note="Rad50/SbcC-type AAA"
FT /evidence="ECO:0000259|Pfam:PF13476"
FT COILED 172..456
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 489..519
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 559..688
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 712..807
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 963 AA; 114602 MW; 1F58C374DB0E6F4D CRC64;
MKPILLKLEN FTTYKKLQEI DFSDLNFFII QGRTGAGKTS IIDAMCYALY GKVPRYKGTS
IHEHLLSKGQ KRMRVYFEFS VKGKRYAVDR QYEPSKPPMV RFYEGSRLLN LKVREVEDYV
SKLLGMDYET FTKVLVLPQG QFDRFLKPQR PAERREILNR LLGYDEIFER ISSIIKETLK
ELEREKGILE AEYESLKSIN QTMLEQKEKE LKRKQEEFKS IRDQKERLSD ELQKAIEKER
LENELSQKTF QLSQLLNKHG EINQKKEKLE KAKRVIIYWP LVREYESILN QKDRIIKEKK
ELQHELIKYS EEIKSVQEEY EKIEEKYKKL DKMREKINHL EIKKEKLNNL ESIKRKIYET
NMEISKSEEE LQNISNSLTD LNEKLQQQNN YLSDLEEKLK NLEGIEAKYA KAQQLKPMYD
SIPKIDEYIK RIDKDIQQKE IELSEVQSKI RQLEDKLFEE YIHQIRLKLS PGDTCPVCGN
KVENVYMVSL EMRTSVENVK EEIQNLRQKE HKLVELLSEK RTQKNSLIQK KEEIISYTKL
DFQEFQKRYR TLEENYKTFL SLREKEKACR EKLQKLKEEK SSKEVELSKL ETSIKHSQRL
LAQLQEEEER LLKEIGEPVI DPARSVRRLE DELKNLKEEI NSIQKRYEEV SRYLKELSAD
FERIKVQMEG KERQEEELKE RLNQLACELY PAFQEFGDLE TLKSFYLPED EIQKLDKEIN
NYERDMESLK RDISLLQERI AGYPKHISKE DLERKVKGLE QIMYKINEEI GFLSRELVDI
KHKIQRREHI EKQLQNISRE LWKYETLQRD MRSENFPEFV SRQMLQTITD RASFYLLKFS
SGTYEFKLNE GDLLVIDRSS GHERSVFTLS GGETFLASLS LAFAVSDIVS HNAPLESIFI
DEGFGSLDRE TRESLGEFFE LIKLNAGRMV GIISHLEDLA EKFDQRVLVE KHGDYSVVKV
KVM
//
