ID D3DIH3_HYDTT Unreviewed; 388 AA.
AC D3DIH3;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=General secretion pathway protein F/pilus assembly protein {ECO:0000313|EMBL:BAI69625.1};
GN OrderedLocusNames=HTH_1171 {ECO:0000313|EMBL:BAI69625.1};
OS Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6).
OC Bacteria; Aquificota; Aquificae; Aquificales; Aquificaceae;
OC Hydrogenobacter.
OX NCBI_TaxID=608538 {ECO:0000313|EMBL:BAI69625.1, ECO:0000313|Proteomes:UP000002574};
RN [1] {ECO:0000313|EMBL:BAI69625.1, ECO:0000313|Proteomes:UP000002574}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6534 / IAM 12695 / TK-6 [Tokyo]
RC {ECO:0000313|Proteomes:UP000002574};
RX PubMed=20348262; DOI=10.1128/JB.00158-10;
RA Arai H., Kanbe H., Ishii M., Igarashi Y.;
RT "Complete genome sequence of the thermophilic, obligately
RT chemolithoautotrophic hydrogen-oxidizing bacterium Hydrogenobacter
RT thermophilus TK-6.";
RL J. Bacteriol. 192:2651-2652(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the GSP F family.
CC {ECO:0000256|ARBA:ARBA00005745}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP011112; BAI69625.1; -; Genomic_DNA.
DR RefSeq; WP_012963805.1; NC_017161.1.
DR AlphaFoldDB; D3DIH3; -.
DR STRING; 608538.HTH_1171; -.
DR KEGG; hth:HTH_1171; -.
DR eggNOG; COG1459; Bacteria.
DR OrthoDB; 9805682at2; -.
DR Proteomes; UP000002574; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.81.30; Type II secretion system (T2SS), domain F; 2.
DR InterPro; IPR003004; GspF/PilC.
DR InterPro; IPR018076; T2SS_GspF_dom.
DR InterPro; IPR042094; T2SS_GspF_sf.
DR PANTHER; PTHR30012; GENERAL SECRETION PATHWAY PROTEIN; 1.
DR PANTHER; PTHR30012:SF0; TYPE II SECRETION SYSTEM PROTEIN F-RELATED; 1.
DR Pfam; PF00482; T2SSF; 2.
DR PRINTS; PR00812; BCTERIALGSPF.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002574};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 155..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 58..178
FT /note="Type II secretion system protein GspF"
FT /evidence="ECO:0000259|Pfam:PF00482"
FT DOMAIN 260..379
FT /note="Type II secretion system protein GspF"
FT /evidence="ECO:0000259|Pfam:PF00482"
SQ SEQUENCE 388 AA; 43896 MW; 96C515B0AFF3B304 CRC64;
MVFSYKGLYN GSLVEGLLEA DTKAEAVSKL KAQNIKVISL KEVSLKESRK DTKFLERFTS
NLLQLLKSGL TVDKALLFIA ERERKYHQKL LKVYEEIRSG STLSMALRLS NLFPDFYVQM
IRSAEESGSL EETLSLILDF IKEENELKSS IITAMLYPSF VFGVSLFSLL IISSYVVPKF
RLVFQSTDVK LPLLTRAMFF LTDIINYLIV GALVVLLLLF VYLRYALRKR HQRLKLESFL
YKLPLLGKLL LNTELIRTFQ TLYTLIKGGV TLNHALDLAG NVPITLRMKD AIRAVRNDVV
KGSSLSKAMK SHQLFPDMVT EMVAVGEQTG ELAGAFYQIY TTYNEEFKTS VKRFVSLLEP
AIILFMGLIV GIIVFSMILA VFSLSEGL
//
