ID D3DJF6_HYDTT Unreviewed; 341 AA.
AC D3DJF6;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Cation efflux system {ECO:0000313|EMBL:BAI69958.1};
GN OrderedLocusNames=HTH_1508 {ECO:0000313|EMBL:BAI69958.1};
OS Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6).
OC Bacteria; Aquificota; Aquificae; Aquificales; Aquificaceae;
OC Hydrogenobacter.
OX NCBI_TaxID=608538 {ECO:0000313|EMBL:BAI69958.1, ECO:0000313|Proteomes:UP000002574};
RN [1] {ECO:0000313|EMBL:BAI69958.1, ECO:0000313|Proteomes:UP000002574}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6534 / IAM 12695 / TK-6 [Tokyo]
RC {ECO:0000313|Proteomes:UP000002574};
RX PubMed=20348262; DOI=10.1128/JB.00158-10;
RA Arai H., Kanbe H., Ishii M., Igarashi Y.;
RT "Complete genome sequence of the thermophilic, obligately
RT chemolithoautotrophic hydrogen-oxidizing bacterium Hydrogenobacter
RT thermophilus TK-6.";
RL J. Bacteriol. 192:2651-2652(2010).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; AP011112; BAI69958.1; -; Genomic_DNA.
DR RefSeq; WP_012964138.1; NC_017161.1.
DR AlphaFoldDB; D3DJF6; -.
DR STRING; 608538.HTH_1508; -.
DR KEGG; hth:HTH_1508; -.
DR eggNOG; COG0845; Bacteria.
DR OrthoDB; 11589at2; -.
DR Proteomes; UP000002574; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30097; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR PANTHER; PTHR30097:SF4; SLR6042 PROTEIN; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002574}.
FT DOMAIN 41..265
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 93..120
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 341 AA; 38400 MW; C3961D3354FA9978 CRC64;
MRVLFIIMLP VLVFSETLKL DQNVIQKLGI KLHTVKIERV KDSLTLPSKV SEYSGLVAEV
FPPVSGVVKK VFVKEGDKVK KGAPLALVYS PQIADLQAQI RMAKVKLQTA QETLKREEML
YREEVIPYAR YYGAKIDYER AKGEYEALLA SLRSFGEVIN DTVLIRSPIS GYVIEQKVFT
GSGVDISKEM FKVHSHEKLW VYAYATPEDA TRVKVGMVGY VLWQGQRLEG KVDYVSHEVD
PNTKRVPVRL LVNNVRDLLR PGLMVQTTIE LGSVSGVWLP LQAVQKVNGR DVVFVKIPEG
FSVKTVRKIR QEGEWVLVEG LKEGQQVATS GLVFLKSQVE R
//
