ID D3E2L4_METRM Unreviewed; 331 AA.
AC D3E2L4;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Bifunctional short chain isoprenyl diphosphate synthase IdsA {ECO:0000313|EMBL:ADC46775.1};
DE EC=2.5.1.1 {ECO:0000313|EMBL:ADC46775.1};
GN Name=idsA {ECO:0000313|EMBL:ADC46775.1};
GN OrderedLocusNames=mru_0924 {ECO:0000313|EMBL:ADC46775.1};
OS Methanobrevibacter ruminantium (strain ATCC 35063 / DSM 1093 / JCM 13430 /
OS OCM 146 / M1) (Methanobacterium ruminantium).
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanobrevibacter.
OX NCBI_TaxID=634498 {ECO:0000313|EMBL:ADC46775.1, ECO:0000313|Proteomes:UP000008680};
RN [1] {ECO:0000313|EMBL:ADC46775.1, ECO:0000313|Proteomes:UP000008680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35063 / DSM 1093 / JCM 13430 / OCM 146 / M1
RC {ECO:0000313|Proteomes:UP000008680};
RX PubMed=20126622; DOI=10.1371/journal.pone.0008926;
RA Leahy S.C., Kelly W.J., Altermann E., Ronimus R.S., Yeoman C.J.,
RA Pacheco D.M., Li D., Kong Z., McTavish S., Sang C., Lambie S.C.,
RA Janssen P.H., Dey D., Attwood G.T.;
RT "The genome sequence of the rumen methanogen Methanobrevibacter ruminantium
RT reveals new possibilities for controlling ruminant methane emissions.";
RL PLoS ONE 5:E8926-E8926(2010).
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
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DR EMBL; CP001719; ADC46775.1; -; Genomic_DNA.
DR RefSeq; WP_012955726.1; NC_013790.1.
DR AlphaFoldDB; D3E2L4; -.
DR STRING; 634498.mru_0924; -.
DR GeneID; 8770576; -.
DR KEGG; mru:mru_0924; -.
DR PATRIC; fig|634498.28.peg.926; -.
DR eggNOG; arCOG01726; Archaea.
DR HOGENOM; CLU_014015_2_1_2; -.
DR OrthoDB; 26738at2157; -.
DR Proteomes; UP000008680; Chromosome.
DR GO; GO:0004161; F:dimethylallyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR NCBIfam; NF040789; gerfarn_diphsyn; 1.
DR NCBIfam; NF040698; IdsA_Meth; 1.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001:SF69; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000008680};
KW Transferase {ECO:0000256|RuleBase:RU004466, ECO:0000313|EMBL:ADC46775.1}.
SQ SEQUENCE 331 AA; 35937 MW; 81B78812A43345EC CRC64;
MSDVTDVLKE YSADVIKTIE ENLAPVQPQN LQDACIYLTK AGGKMLRPAL TLISCEAVGG
NKEDALKTAA AIELIHTFSL IHDDIMDDDD MRRGMPSVHK VWDEPLAILA GDTLFSKAFE
MIISSKEENA HPEHVANALA TVADACVKIC EGQASDMSFE GDFDVKEAEY SEMIYKKTGA
LIAAATKAGA IMGGADEKEV TALYEYGRMI GIAFQIQDDY LDVISDEKDL GKPVGSDIAK
GKMTLMVVKA LAESDGEDHE RLLEILKDND CSQDMVNEAI DLFNKYGSID YAYNLALENV
NGAKEAIAFL PDSDAKSMLI ALADFVIARS S
//
