ID   D3GD96_GALME            Unreviewed;       357 AA.
AC   D3GD96;
DT   23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   23-MAR-2010, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=Inhibitor of apoptosis protein {ECO:0000313|EMBL:ACV04797.1};
GN   Name=IAP {ECO:0000313|EMBL:ACV04797.1};
OS   Galleria mellonella (Greater wax moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Pyraloidea;
OC   Pyralidae; Galleriinae; Galleria.
OX   NCBI_TaxID=7137 {ECO:0000313|EMBL:ACV04797.1};
RN   [1] {ECO:0000313|EMBL:ACV04797.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=22975212; DOI=10.1016/j.gene.2012.08.036;
RA   Khoa D.B., Takeda M.;
RT   "Expression analysis of inhibitor of apoptosis and related caspases in the
RT   midgut and silk gland of the greater wax moth, Galleria mellonella, during
RT   metamorphosis and under starvation.";
RL   Gene 510:133-141(2012).
CC   -!- SIMILARITY: Belongs to the IAP family. {ECO:0000256|ARBA:ARBA00006672}.
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DR   EMBL; FJ643490; ACV04797.1; -; mRNA.
DR   AlphaFoldDB; D3GD96; -.
DR   GO; GO:0043067; P:regulation of programmed cell death; IEA:UniProt.
DR   CDD; cd00022; BIR; 2.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR001370; BIR_rpt.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR10044:SF139; DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2; 1.
DR   PANTHER; PTHR10044; INHIBITOR OF APOPTOSIS; 1.
DR   Pfam; PF00653; BIR; 2.
DR   Pfam; PF13920; zf-C3HC4_3; 1.
DR   SMART; SM00238; BIR; 2.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF57924; Inhibitor of apoptosis (IAP) repeat; 2.
DR   PROSITE; PS50143; BIR_REPEAT_2; 2.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   2: Evidence at transcript level;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          310..345
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          29..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          276..299
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        29..49
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   357 AA;  40096 MW;  668649A5C26CFD25 CRC64;
     MSNSVAALDS YTAAVETSFK NKDIHKLHCS TPSSSSTSSS TSFTSTPSPD KIDNRDRFNY
     CEVDKMQNVE ERLKSFVNWP VPFLSPEKLA QCGFYYKGCG DEVICAYCNV EIMSWREGDD
     PAVDHKRWSP QCPLLRMESD TDNLSSCLLR RQPSTANLPI SSTSTSGHDE CGTRALPTKA
     TPVHPQYATK AARLRTFNDW PLSMPQKPED LADAGFYCTG KGDQTKCYFC NGGLKDWEKD
     DIPWEQHAKW FSRCYFVYLV KGREYVQKVL NSTQNNVSQT TQEKPETKTI PAAPTSSNSN
     IELEDTRKLC KVCYEDECNV VIVPCGHVCA CAKCVLSTDR CPICRGSIDN TLRLYFS
//