ID D3GGR9_9POAL Unreviewed; 203 AA.
AC D3GGR9;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Alcohol dehydrogenase 1 {ECO:0000256|ARBA:ARBA00041139};
DE EC=1.1.1.1 {ECO:0000256|ARBA:ARBA00013190};
DE Flags: Fragment;
GN Name=adh1 {ECO:0000313|EMBL:ACY25493.1};
OS Kengyilia rigidula.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Hordeinae; Kengyilia.
OX NCBI_TaxID=103742 {ECO:0000313|EMBL:ACY25493.1};
RN [1] {ECO:0000313|EMBL:ACY25493.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ZY3113 {ECO:0000313|EMBL:ACY25493.1};
RX PubMed=19885741; DOI=10.1007/s11033-009-9909-4;
RA Liu Q., Zhang N., Li L., Liu J.;
RT "Identification of Elymus (Triticeae, Poaceae) and its related genera
RT genomes by RFLP analysis of PCR-amplified Adh genes.";
RL Mol. Biol. Rep. 37:3249-3257(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH;
CC Xref=Rhea:RHEA:10736, ChEBI:CHEBI:15378, ChEBI:CHEBI:15734,
CC ChEBI:CHEBI:17478, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.1.1.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001146};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a secondary alcohol + NAD(+) = a ketone + H(+) + NADH;
CC Xref=Rhea:RHEA:10740, ChEBI:CHEBI:15378, ChEBI:CHEBI:17087,
CC ChEBI:CHEBI:35681, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.1.1.1;
CC Evidence={ECO:0000256|ARBA:ARBA00000781};
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00008072}.
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DR EMBL; FJ746040; ACY25493.1; -; Genomic_DNA.
DR AlphaFoldDB; D3GGR9; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43880; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR43880:SF63; ALCOHOL DEHYDROGENASE 1; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 5..74
FT /note="Alcohol dehydrogenase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08240"
FT DOMAIN 148..200
FT /note="Alcohol dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00107"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACY25493.1"
FT NON_TER 203
FT /evidence="ECO:0000313|EMBL:ACY25493.1"
SQ SEQUENCE 203 AA; 21321 MW; F5CF7F844F16CE3E CRC64;
GQTPMFPRIF GHEAGDIVES VGEGVTDVAP GDHVLPVFTG ECKECPHCKS AESNMCDLLR
INTDRGVMIG DGKSRFSIDG KPIYHFVGTS TFSEYTVMHV GCVAKINPEA PLDKVCVLSC
GISTGLGASI NVAKPPKGST VAIFGLGAVG LAAAEGARIA GASRIIGIDL NASRFEEARK
FGCTEFVNPK DHSKPVQQVL AEM
//
