ID   D3HR37_LEGLN            Unreviewed;       322 AA.
AC   D3HR37;
DT   23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   23-MAR-2010, sequence version 1.
DT   27-MAR-2024, entry version 65.
DE   RecName: Full=Guanylate cyclase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=LLO_1012 {ECO:0000313|EMBL:CBJ11364.1};
OS   Legionella longbeachae serogroup 1 (strain NSW150).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=661367 {ECO:0000313|EMBL:CBJ11364.1, ECO:0000313|Proteomes:UP000001060};
RN   [1] {ECO:0000313|EMBL:CBJ11364.1, ECO:0000313|Proteomes:UP000001060}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NSW150 {ECO:0000313|EMBL:CBJ11364.1,
RC   ECO:0000313|Proteomes:UP000001060};
RX   PubMed=20174605; DOI=10.1371/journal.pgen.1000851;
RA   Cazalet C., Gomez-Valero L., Rusniok C., Lomma M., Dervins-Ravault D.,
RA   Newton H., Sansom F., Jarraud S., Zidane N., Ma L., Bouchier C.,
RA   Etienne J., Hartland E., Buchrieser C.;
RT   "Analysis of the Legionella longbeachae genome and transcriptome uncovers
RT   unique strategies to cause Legionnaires' disease.";
RL   PLoS Genet. 6:E1000851-E1000851(2010).
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DR   EMBL; FN650140; CBJ11364.1; -; Genomic_DNA.
DR   RefSeq; WP_003632328.1; NC_013861.1.
DR   AlphaFoldDB; D3HR37; -.
DR   STRING; 661367.LLO_1012; -.
DR   KEGG; llo:LLO_1012; -.
DR   eggNOG; COG2114; Bacteria.
DR   HOGENOM; CLU_862741_0_0_6; -.
DR   OrthoDB; 8196020at2; -.
DR   Proteomes; UP000001060; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001060};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        17..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        74..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   322 AA;  36760 MW;  8FC6E3257176BEDE CRC64;
     MKAIYLFGLF ILRGLKLLVW CLILTIFLGI VAPYVGNLSS YPYLKPVIQT DKVLNTTIKH
     YVPTRIANWD LSRVIPIVGL LFISSIISGY ILSLQKIKMK VNLEEFKNRA ITKEQQTLVK
     KMEETIDKPG KLKEKNRQTL LKEFIQLKKE LEKTGRNLSF LAIDVVDSTN MKIGEDPVIV
     ENDFNQYHDF IVCKFKEHGY IKAAWTPDGV MSCFNTTEQA FEAAKDILSS LPDFNKSTKM
     MKQDFHVRCG INTGFVYYDL STPLEEFSDR VIDIAGHMQK HAPPDTVLVA KDLVKPIESQ
     EVFVPTKNIV DGLEACEWRS SN
//