ID D3HYV6_9BACT Unreviewed; 1375 AA.
AC D3HYV6;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Kinase domain protein {ECO:0000313|EMBL:EFC75575.1};
GN ORFNames=HMPREF0649_01438 {ECO:0000313|EMBL:EFC75575.1};
OS Segatella buccae D17.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Segatella.
OX NCBI_TaxID=575611 {ECO:0000313|EMBL:EFC75575.1, ECO:0000313|Proteomes:UP000005080};
RN [1] {ECO:0000313|EMBL:EFC75575.1, ECO:0000313|Proteomes:UP000005080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D17 {ECO:0000313|EMBL:EFC75575.1,
RC ECO:0000313|Proteomes:UP000005080};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Feldgarden M., Earl A., Young S.K., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J.,
RA Yandava C., Sibley C.D., White A., Allen-Vercoe E., Strauss J., Crowley S.,
RA Surette M.G., Haas B., Nusbaum C., Birren B.;
RT "The Genome Sequence of Prevotella buccae Oral Taxon 560 strain D17.";
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG739934; EFC75575.1; -; Genomic_DNA.
DR RefSeq; WP_004342130.1; NZ_GG739934.1.
DR HOGENOM; CLU_255503_0_0_10; -.
DR OrthoDB; 9813021at2; -.
DR Proteomes; UP000005080; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0010506; P:regulation of autophagy; IEA:InterPro.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 2.
DR InterPro; IPR045269; Atg1-like.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR011528; NERD.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008266; Tyr_kinase_AS.
DR PANTHER; PTHR24348:SF22; NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE; 1.
DR PANTHER; PTHR24348; SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED; 1.
DR Pfam; PF08378; NERD; 1.
DR Pfam; PF00069; Pkinase; 2.
DR SMART; SM00220; S_TKc; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 2.
DR PROSITE; PS50965; NERD; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 2.
DR PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Kinase {ECO:0000313|EMBL:EFC75575.1};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Transferase {ECO:0000313|EMBL:EFC75575.1}.
FT DOMAIN 13..128
FT /note="NERD"
FT /evidence="ECO:0000259|PROSITE:PS50965"
FT DOMAIN 175..464
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 509..761
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 538
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1375 AA; 158510 MW; DB36FE3E146A9995 CRC64;
MAQIRKPIHD DGPVNAGEQR LLDYLDLKLP SNYIIIPNLN IAITGQNRVM KYWEYDCIVV
APHAVYHIEN KDWAGNLEGD DWAWFRSGQE VTNPHKTAGL KSRILASKIK NQHPDWRFGQ
ILTAITLSHP QQSKFGLDPT CDCYKQTFTL GEDLIDVLTK PELVGRTPGM IMDIQSQLVD
LLSGQSVERR RAERKEIFNY LIEEVLQETE EFTEYLCVPK LIATARYKVR EYPLDVVGKS
PEELNKLSLM VQNASFAQDK IGASPFIVKT DCRMNEEQTY YYEISRYQDE SSLRSKLRQK
TFKQTDKISI ILDVANALKA AHKEQVYHRD VCPENIFVYE GGKAALANFG MAWFVEHSDL
SFTVKKDTNI NSPYTAPEFL EGDVCSGSDI FALGVIFYEL MTGKLPFDSC LTFTSALGGV
LTEDLMPSKV SKDLPEWMDE VVKHTIVADP FKRWQEADEF IEFINNSMEE EQKKTIEAQN
AEAGNNTTSQ PKDAYLKDMK PGVKVTPSMT LHEILGRGGF GRVFKVWHDM QKQFLAIKIF
ERDASVDNAI NEFEALKSLH HPNIVEFKFN DRTQQGLFYT LMELLEGENL QDYTRGDLRL
PVDEVYKMST QILKALRYMQ EEQNPPVYHR DIKPSNIMWH KRQIYKLIDF NISTTTDDDK
SFGGTFPYMA PDLVLSGNKI DWDKSADTFA LGITIYELLA HAYPWPGSNM RPNIHMQPTD
IRSYNDKLTN EIAEFIMKAI ITDRHKRFTS AKEMLEALEK IGVNGILKDT STIINTSTVN
ANPVDYINSL YSQSRHGNNG TRAGAKTHAF DDLTYTKTKL DKQLIQDIKN LKYKLIIITG
NAGDGKTAFI HRIEDQGTNK ESFSTNNGSQ FYINGIRFES NYDGSQDEDE KANDKVLAQF
LSPFNNLSDY TQAQEGRVIA INEGRLVDFL STHDELKKLR DNIEDYFYQE GHAELLPGLM
VINLNLRSVT ARDGNSPSLL AQQVKKLTRP ELWSKCEGCP IADRCYIKYN VDTFQDSSAG
DEVINRLEWL VRTIFYKREL HITMRDLRSM IAWMLTRDYS CDEVKQLVEY VQTAQLPEYY
WQYYYFNLTA PVAWPAKDFM LPSLDSNDRL VKLLRETDVA GVALPAYDRD LYYTSKRPND
YLIFSDRKRS LLNDFNENNV IIPAYEVKSD VIRMQATGRH KSYVRHQYFE GKFNFRRRLP
YRYASMFEEQ LRVEDERALK ETMQDLACAI SASEGCDNAR LTEGYLLLAS SNVGDPISKS
YRRFPLDEFE LFVNKTEHLT KYIEYESDSL TFRHKTDKFI QLTVSLDLYE MLQYIRAGFS
PSVNDLRGRF IELQIFKNLL EAKTYTEILV TKNNRKFTVI RLDGKKHIVI EPLNA
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