ID D3JUF7_9BACT Unreviewed; 249 AA.
AC D3JUF7;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 22-FEB-2023, entry version 18.
DE SubName: Full=Methyl coenzyme M reductase alpha subunit {ECO:0000313|EMBL:ADB29056.1};
DE Flags: Fragment;
GN Name=mcrA {ECO:0000313|EMBL:ADB29056.1};
OS uncultured bacterium.
OC Bacteria; environmental samples.
OX NCBI_TaxID=77133 {ECO:0000313|EMBL:ADB29056.1};
RN [1] {ECO:0000313|EMBL:ADB29056.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=20090951; DOI=10.1371/journal.pone.0008738;
RA Lloyd K.G., Albert D.B., Biddle J.F., Chanton J.P., Pizarro O., Teske A.;
RT "Spatial structure and activity of sedimentary microbial communities
RT underlying a Beggiatoa spp. mat in a Gulf of Mexico hydrocarbon seep.";
RL PLoS ONE 5:E8738-E8738(2010).
CC -!- SIMILARITY: Belongs to the methyl-coenzyme M reductase alpha subunit
CC family. {ECO:0000256|ARBA:ARBA00010434}.
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DR EMBL; GU302503; ADB29056.1; -; mRNA.
DR AlphaFoldDB; D3JUF7; -.
DR GO; GO:0050524; F:coenzyme-B sulfoethylthiotransferase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0015948; P:methanogenesis; IEA:InterPro.
DR Gene3D; 3.30.70.470; -; 1.
DR Gene3D; 1.20.840.10; Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal; 1.
DR InterPro; IPR008924; Me_CoM_Rdtase_asu/bsu_C.
DR InterPro; IPR009047; Me_CoM_Rdtase_asu_C.
DR InterPro; IPR003183; Me_CoM_Rdtase_asu_N.
DR InterPro; IPR015823; Me_CoM_Rdtase_asu_N_sub2.
DR InterPro; IPR009024; Me_CoM_Rdtase_Fd-like_fold.
DR Pfam; PF02249; MCR_alpha; 1.
DR Pfam; PF02745; MCR_alpha_N; 1.
DR SUPFAM; SSF48081; Methyl-coenzyme M reductase alpha and beta chain C-terminal domain; 1.
DR SUPFAM; SSF55088; Methyl-coenzyme M reductase subunits; 1.
PE 2: Evidence at transcript level;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Nickel {ECO:0000256|ARBA:ARBA00022596}.
FT DOMAIN 1..41
FT /note="Methyl-coenzyme M reductase alpha subunit N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF02745"
FT DOMAIN 89..217
FT /note="Methyl-coenzyme M reductase alpha subunit C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF02249"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADB29056.1"
FT NON_TER 249
FT /evidence="ECO:0000313|EMBL:ADB29056.1"
SQ SEQUENCE 249 AA; 26807 MW; 3A1B05AF4CEB517C CRC64;
AMQIGMSFIS AYHMCAGEAA VADLAFTAKH AGLIEMSEML PARRARGPNE PGGLSFGHMC
DIVQTSRKFR DDPCKIALET CAAAMMLYDQ IWLGGYMSGG VGFTMYATAA YTNNTVDDNL
YADTEYGWDT YGTSIGNVKA PTLDIIKDIG TWGALYGLEL YENYPTALED HFGGSQRATV
ISTATGAACA ITTGNSNAGL SAWYLSMYLH KEAHGRLGFF GYDLQDQCGA TNVFSYQSDE
GLLAEMRGA
//
