ID   D3KVK3_STRPY            Unreviewed;       280 AA.
AC   D3KVK3;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   24-JAN-2024, entry version 39.
DE   SubName: Full=Putative transcription regulator {ECO:0000313|EMBL:BAI78828.1};
GN   Name=rgg {ECO:0000313|EMBL:BAI78828.1};
OS   Streptococcus pyogenes.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1314 {ECO:0000313|EMBL:BAI78828.1};
RN   [1] {ECO:0000313|EMBL:BAI78828.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NIH372 {ECO:0000313|EMBL:BAI78828.1};
RX   PubMed=20368967; DOI=10.1371/journal.ppat.1000832;
RA   Ikebe T., Ato M., Matsumura T., Hasegawa H., Sata T., Kobayashi K.,
RA   Watanabe H.;
RT   "Highly frequent mutations in negative regulators of multiple virulence
RT   genes in group A streptococcal toxic shock syndrome isolates.";
RL   PLoS Pathog. 6:e1000832-e1000832(2010).
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DR   EMBL; AB517860; BAI78828.1; -; Genomic_DNA.
DR   AlphaFoldDB; D3KVK3; -.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR010057; Transcription_activator_Rgg_C.
DR   NCBIfam; TIGR01716; RGG_Cterm; 1.
DR   PANTHER; PTHR37038; TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR   Pfam; PF21259; Rgg_C; 1.
DR   SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
PE   4: Predicted;
FT   DOMAIN          92..269
FT                   /note="HTH-type transcriptional regulator Rgg C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21259"
SQ   SEQUENCE   280 AA;  33298 MW;  A30F17604B3CC302 CRC64;
     MEIGETVEFI RHSKNISIKQ VCGDYLTRQT YYRFIKNNLD ISSKKLLYIL DNLNVNVDEF
     LFISNNFKQY KEFIDMDTAK HYFECRNIEG LNHILDSYKD SKSTKEKNLF ALVKVLLATL
     TEEDCLTERT YLSNYLINIE TWSHYETVLF NNCMFIFESC FIEMVFSKVI LNLDKYNTLR
     YYGNESIRMF VNMLILFIQR QEYDKASEIL AKIEDYQLND DCLYERCCVS FFDGIIGLIN
     GKEGTEQKCV QILEIFQLLN CKTIHHMFQT YLEAIKHKLS
//