ID D3NUG5_AZOS1 Unreviewed; 353 AA.
AC D3NUG5;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN OrderedLocusNames=AZL_014060 {ECO:0000313|EMBL:BAI72044.1};
OS Azospirillum sp. (strain B510).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Azospirillaceae; Azospirillum.
OX NCBI_TaxID=137722 {ECO:0000313|EMBL:BAI72044.1, ECO:0000313|Proteomes:UP000002040};
RN [1] {ECO:0000313|EMBL:BAI72044.1, ECO:0000313|Proteomes:UP000002040}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B510 {ECO:0000313|EMBL:BAI72044.1,
RC ECO:0000313|Proteomes:UP000002040};
RX PubMed=20047946; DOI=10.1093/dnares/dsp026;
RA Kaneko T., Minamisawa K., Isawa T., Nakatsukasa H., Mitsui H.,
RA Kawaharada Y., Nakamura Y., Watanabe A., Kawashima K., Ono A., Shimizu Y.,
RA Takahashi C., Minami C., Fujishiro T., Kohara M., Katoh M., Nakazaki N.,
RA Nakayama S., Yamada M., Tabata S., Sato S.;
RT "Complete genomic structure of the cultivated rice endophyte Azospirillum
RT sp. B510.";
RL DNA Res. 17:37-50(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
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DR EMBL; AP010946; BAI72044.1; -; Genomic_DNA.
DR RefSeq; WP_012974023.1; NC_013854.1.
DR AlphaFoldDB; D3NUG5; -.
DR STRING; 137722.AZL_014060; -.
DR KEGG; azl:AZL_014060; -.
DR HOGENOM; CLU_009834_22_1_5; -.
DR OrthoDB; 9790967at2; -.
DR Proteomes; UP000002040; Chromosome.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:BAI72044.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002040}.
FT DOMAIN 15..341
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 353 AA; 37493 MW; 539E11EF102DB3B1 CRC64;
MSDDAEILFE RRGAIGLVTL NRPKALNALT LGMIRLFDPQ LRAWDADPEV KAVVIRGAGE
KAFCAGGDVV SLYEAGKAAK EGRGDTSPIR AFFSEEYVLN RLIKRLSKPY VAVIDGISMG
GGVGLSVHGS HRIVTERTLF AMPETGIGLY PDVGGTYFLP RLPGQVGVWL GLTGDRLKAA
DLLAIGAADA FVPSGEIDGL IGDLAAGRPA DEAIATRRGD AGEAMVRALR AVIDRCYAFD
SVEAIVKALE AEGGDWANGQ LATLRRVSPT SLKVTLAALR RGAGLDFDGC MVQELRLSLA
CLAGVDFYEG IRAVLVDKDK SPKWKPANLA DVGPSDVARH FTEPAGGDLL FRD
//
