ID D3P619_AZOS1 Unreviewed; 933 AA.
AC D3P619;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=AZL_d02720 {ECO:0000313|EMBL:BAI76098.1};
OS Azospirillum sp. (strain B510).
OG Plasmid pAB510d {ECO:0000313|EMBL:BAI76098.1,
OG ECO:0000313|Proteomes:UP000002040}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Azospirillaceae; Azospirillum.
OX NCBI_TaxID=137722 {ECO:0000313|EMBL:BAI76098.1, ECO:0000313|Proteomes:UP000002040};
RN [1] {ECO:0000313|EMBL:BAI76098.1, ECO:0000313|Proteomes:UP000002040}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B510 {ECO:0000313|EMBL:BAI76098.1,
RC ECO:0000313|Proteomes:UP000002040};
RC PLASMID=pAB510d {ECO:0000313|EMBL:BAI76098.1};
RX PubMed=20047946; DOI=10.1093/dnares/dsp026;
RA Kaneko T., Minamisawa K., Isawa T., Nakatsukasa H., Mitsui H.,
RA Kawaharada Y., Nakamura Y., Watanabe A., Kawashima K., Ono A., Shimizu Y.,
RA Takahashi C., Minami C., Fujishiro T., Kohara M., Katoh M., Nakazaki N.,
RA Nakayama S., Yamada M., Tabata S., Sato S.;
RT "Complete genomic structure of the cultivated rice endophyte Azospirillum
RT sp. B510.";
RL DNA Res. 17:37-50(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AP010950; BAI76098.1; -; Genomic_DNA.
DR RefSeq; WP_012977904.1; NC_013858.1.
DR AlphaFoldDB; D3P619; -.
DR KEGG; azl:AZL_d02720; -.
DR HOGENOM; CLU_000445_104_15_5; -.
DR OrthoDB; 9810730at2; -.
DR Proteomes; UP000002040; Plasmid pAB510d.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.20.120.160; HPT domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR036641; HPT_dom_sf.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR008207; Sig_transdc_His_kin_Hpt_dom.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR45339; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR PANTHER; PTHR45339:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF01627; Hpt; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47226; Histidine-containing phosphotransfer domain, HPT domain; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Plasmid {ECO:0000313|EMBL:BAI76098.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002040};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 166..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 185..237
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 394..627
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 657..774
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 236..263
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 706
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 933 AA; 98937 MW; DF059E07D3AEEE21 CRC64;
MILTRLAPWK TLRGRMLAAA MAVEAIMLTL MVANSVRLLY GSLAEQAKLH AEQVAPVLNA
ALVAPLAQRD YATLQAVLDE SRTNGGVVYL AVSDSKGKLV AISGWPQGRA LPDPDPSLTL
DAKDGEARYD VAVPVSLAGQ KLGAVQFGLD LLHIVQARRD LLTQGIAIAL SEILLSAGLL
TLLGLWLTRH LAALARASER VAAGDYSPPD LAEGNDDIGR LGAAFNTMSH AIKERVDQLT
VALDEQEALA RDMEQERARL SALLSAMDFG VLFVGGDGRI AYANPAFSTL FSIAGAPVGH
RLDETLANAG NAPLDTDHAL LSAVDADERR EMTLTDGRIV GWHNVPVRNA AGAAIGKLWL
CIDVTEPRRA AEQLFQAKEK AEAASRSKTE FLATVSHELR TPMNGVLGNL TLLADASLPA
EEKRLADVAR RSAETLLRLL DDILDLSKLE ARRIDLEEAD CALPQLIDGV LELLRPSATD
KGLDLSARLT PSVPEVIVTD PARLRQILFN LVGNAVKFTE DGHIAVRVRR LEPGPDIGAD
IGVDGHPDSV LLEFEVEDTG IGIAPDSVPT LFDRFTQADS SITRRYGGTG LGLAICRDLC
LLMGGGITVE TAPGRGSVFR FTIIARPGDP SALRRVDPAH GTGVGEAARV AALPPLRVLA
VDDIEVNRDI VRGILERAGH SVALAASGGE AVRLVRERDF DLVLMDIQMP GMDGLTATRR
LRDLPDPKGR IPILALTAHA SGSSRPECLS AGMNGFVTKP LRPTLLFAEM AAALGGDAAA
PAPSFGGSAP APATPEAVLP LVPDIPAADL PEPDLLDPDL LDGEQVSLLL EVLTAEDWAA
SVAGFTDNGR KTIDSMVAQA RAGEPHNRTA HTLKGTSLNL GAAALGRLAK ELEHAPAAMV
LTQEGRLYDL LDRSLAELRL RRPPPPAGER PNG
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