ID D3PL20_MEIRD Unreviewed; 646 AA.
AC D3PL20;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:AGK03370.1};
GN OrderedLocusNames=Mrub_0136 {ECO:0000313|EMBL:ADD26916.1};
GN ORFNames=K649_00290 {ECO:0000313|EMBL:AGK03370.1};
OS Meiothermus ruber (strain ATCC 35948 / DSM 1279 / VKM B-1258 / 21) (Thermus
OS ruber).
OC Bacteria; Deinococcota; Deinococci; Thermales; Thermaceae; Meiothermus.
OX NCBI_TaxID=504728 {ECO:0000313|EMBL:AGK03370.1, ECO:0000313|Proteomes:UP000013026};
RN [1] {ECO:0000313|EMBL:ADD26916.1, ECO:0000313|Proteomes:UP000006655}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35948 / DSM 1279 / VKM B-1258 / 21
RC {ECO:0000313|Proteomes:UP000006655}, and DSM 1279
RC {ECO:0000313|EMBL:ADD26916.1};
RX PubMed=21304689; DOI=10.4056/sigs.1032748;
RA Tindall B.J., Sikorski J., Lucas S., Goltsman E., Copeland A.,
RA Glavina Del Rio T., Nolan M., Tice H., Cheng J.F., Han C., Pitluck S.,
RA Liolios K., Ivanova N., Mavromatis K., Ovchinnikova G., Pati A.,
RA Fahnrich R., Goodwin L., Chen A., Palaniappan K., Land M., Hauser L.,
RA Chang Y.J., Jeffries C.D., Rohde M., Goker M., Woyke T., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.,
RA Lapidus A.;
RT "Complete genome sequence of Meiothermus ruber type strain (21).";
RL Stand. Genomic Sci. 3:26-36(2010).
RN [2] {ECO:0000313|EMBL:AGK03370.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM 1279 {ECO:0000313|EMBL:AGK03370.1};
RA Klammer A., Drake J., Heiner C., Clum A., Copeland A., Huddleston J.,
RA Eichler E., Turner S.W.;
RT "Non-Hybrid, Finished Microbial Genome Assemblies from Long-Read SMRT
RT Sequencing Data.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AGK03370.1, ECO:0000313|Proteomes:UP000013026}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35948 / DSM 1279 / VKM B-1258 / 21
RC {ECO:0000313|Proteomes:UP000013026}, and DSM 1279
RC {ECO:0000313|EMBL:AGK03370.1};
RA Chin J., Alexander D.H., Marks P., Korlach J., Clum A., Copeland A.;
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001743; ADD26916.1; -; Genomic_DNA.
DR EMBL; CP005385; AGK03370.1; -; Genomic_DNA.
DR RefSeq; WP_013012435.1; NC_021081.1.
DR AlphaFoldDB; D3PL20; -.
DR STRING; 504728.K649_00290; -.
DR KEGG; mrb:Mrub_0136; -.
DR KEGG; mre:K649_00290; -.
DR PATRIC; fig|504728.9.peg.62; -.
DR eggNOG; COG1022; Bacteria.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000006655; Chromosome.
DR Proteomes; UP000013026; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd17641; LC_FACS_bac1; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43272:SF83; ACYL-COA SYNTHETASE LONG-CHAIN, ISOFORM J; 1.
DR PANTHER; PTHR43272; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:AGK03370.1}.
FT DOMAIN 18..436
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
SQ SEQUENCE 646 AA; 73212 MW; A5934F75B2B29D64 CRC64;
MMPSGYELKK YTLPQVLQMR AKAMPKQVAI REKDLGIWNE ITFADYYRHV TRFAAGLLAL
GFEKGERLAV IADNIPEWLY AELATQALGG ISVGVYQSSL PPEIAYVLSY TGAAFVVAED
QEQVDKLLEI RSEIPSVRKV IYEDPKGMRA YRDDPWIIGF DEVERLGEEY LQKHPQAVEE
RIAQGHPEDV CHLSLTSGTT GRPKAAMLRH RNLLHMGVAL QEIDPLKPTD DYLSFLPFAW
IGEQMMSVGM ALAGGFAVNM PESVETAMSD LKEIGPHVMF SPPRVWEGTQ SQIWVRISET
YAFNRWVYQQ MLKIGYRAAD YRMRGRPMPL GLRLAYWFAD QIMFKPLRDQ LGFLRLRRAY
TGGAALGPDV FRFYHAIGVN LKQIYGQTEI IGIAFVHRDG DVRADTVGLP IPGGEVKISE
RGEILCRSDA VVAGYWQNPE ATAETFADGW LHTGDAGYLT PEGHLVVIDR VSDVMHTSAQ
QMFSPQFIEN KLKFSPYIKE AVVFGDQKPF LTAFINVDPQ TVGKWAEDRR IAYTTYIDLS
QKPQVAELIR KEVQRVNEGL PEHLRIQRFV LLYKLLDADD DELTRTGKVR RKFIMQRYQP
IVDALYSGTD KVQVDTEFKY QDGTVQKVSV EVRVLEADGK PEIVGV
//
