GenomeNet

Database: UniProt
Entry: D3TQT3_GLOMM
LinkDB: D3TQT3_GLOMM
Original site: D3TQT3_GLOMM 
ID   D3TQT3_GLOMM            Unreviewed;       297 AA.
AC   D3TQT3;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   24-JAN-2024, entry version 43.
DE   RecName: Full=Large ribosomal subunit protein uL18 {ECO:0000256|ARBA:ARBA00035197};
DE   AltName: Full=60S ribosomal protein L5 {ECO:0000256|ARBA:ARBA00035352};
OS   Glossina morsitans morsitans (Savannah tsetse fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=37546 {ECO:0000313|EMBL:ADD20061.1};
RN   [1] {ECO:0000313|EMBL:ADD20061.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Salivary gland {ECO:0000313|EMBL:ADD20061.1};
RX   PubMed=20353571; DOI=10.1186/1471-2164-11-213;
RA   Alves-Silva J., Ribeiro J.M., Van Den Abbeele J., Attardo G., Hao Z.,
RA   Haines L.R., Soares M.B., Berriman M., Aksoy S., Lehane M.J.;
RT   "An insight into the sialome of Glossina morsitans morsitans.";
RL   BMC Genomics 11:213-213(2010).
RN   [2] {ECO:0000313|EMBL:ADD20061.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Salivary gland {ECO:0000313|EMBL:ADD20061.1};
RG   International Glossina Genome Initiative;
RA   da Silva J., Ribeiro J.M.C., Abbeele J.V., Attardo G., Hao Z., Haines L.R.,
RA   Soares M.B., Berriman M., Aksoy S., Lehane M.J.;
RL   Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EnsemblMetazoa:GMOY000366-PA, ECO:0000313|Proteomes:UP000092444}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Yale {ECO:0000313|EnsemblMetazoa:GMOY000366-PA,
RC   ECO:0000313|Proteomes:UP000092444};
RA   Lawson D.;
RT   "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT   Trypanosomiasis.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|Proteomes:UP000092444}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Yale {ECO:0000313|Proteomes:UP000092444};
RG   International Glossina Genome Initiative W.H.O.;
RA   Lawson D.;
RT   "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT   Trypanosomiasis.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [5] {ECO:0000313|EnsemblMetazoa:GMOY000366-PA}
RP   IDENTIFICATION.
RC   STRAIN=Yale {ECO:0000313|EnsemblMetazoa:GMOY000366-PA};
RG   VectorBase;
RL   Submitted (OCT-2016) to UniProtKB.
RN   [6] {ECO:0000313|EnsemblMetazoa:GMOY000366-PA}
RP   IDENTIFICATION.
RC   STRAIN=Yale {ECO:0000313|EnsemblMetazoa:GMOY000366-PA};
RG   EnsemblMetazoa;
RL   Submitted (FEB-2021) to UniProtKB.
CC   -!- FUNCTION: Component of the ribosome, a large ribonucleoprotein complex
CC       responsible for the synthesis of proteins in the cell. The small
CC       ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the
CC       encoded message by selecting cognate aminoacyl-transfer RNA (tRNA)
CC       molecules. The large subunit (LSU) contains the ribosomal catalytic
CC       site termed the peptidyl transferase center (PTC), which catalyzes the
CC       formation of peptide bonds, thereby polymerizing the amino acids
CC       delivered by tRNAs into a polypeptide chain. The nascent polypeptides
CC       leave the ribosome through a tunnel in the LSU and interact with
CC       protein factors that function in enzymatic processing, targeting, and
CC       the membrane insertion of nascent chains at the exit of the ribosomal
CC       tunnel. {ECO:0000256|ARBA:ARBA00004021}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL18 family.
CC       {ECO:0000256|ARBA:ARBA00007116}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CCAG010005354; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; EZ423785; ADD20061.1; -; mRNA.
DR   AlphaFoldDB; D3TQT3; -.
DR   STRING; 37546.D3TQT3; -.
DR   EnsemblMetazoa; GMOY000366-RA; GMOY000366-PA; GMOY000366.
DR   VEuPathDB; VectorBase:GMOY000366; -.
DR   Proteomes; UP000092444; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0008097; F:5S rRNA binding; IEA:InterPro.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   CDD; cd00432; Ribosomal_L18_L5e; 1.
DR   Gene3D; 3.30.420.100; -; 1.
DR   HAMAP; MF_01337_A; Ribosomal_L18_A; 1.
DR   InterPro; IPR005485; Rbsml_uL18_euk/arc.
DR   InterPro; IPR025607; Ribosomal_uL18_C_euk.
DR   PANTHER; PTHR23410:SF12; 60S RIBOSOMAL PROTEIN L5; 1.
DR   PANTHER; PTHR23410; RIBOSOMAL PROTEIN L5-RELATED; 1.
DR   Pfam; PF14204; Ribosomal_L18_c; 1.
DR   Pfam; PF17144; Ribosomal_L5e; 1.
DR   PRINTS; PR00058; RIBOSOMALL5.
DR   SUPFAM; SSF53137; Translational machinery components; 1.
PE   2: Evidence at transcript level;
KW   Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW   Ribosomal protein {ECO:0000256|ARBA:ARBA00022980,
KW   ECO:0000313|EMBL:ADD20061.1}.
FT   DOMAIN          236..289
FT                   /note="Large ribosomal subunit protein uL18 C-terminal
FT                   eukaryotes"
FT                   /evidence="ECO:0000259|Pfam:PF14204"
SQ   SEQUENCE   297 AA;  34114 MW;  D551F71C1B69AE4C CRC64;
     MGFVKVVKNK QYYKRYQVKF RRRREGKTDY YARKRLIFQD KNKYNTPKYR LIVRLSNKDI
     TVQIAYSRIE GDRIICAAYS HELPNYGIKV GLTNYAAAYC TGLLVARRIL NKLGLDSLYD
     GCPEITGDEY NVEPVADGPG AFRCYLDVGL ARTTTGARVF GAMKGAVDGG LNIPHSLKRF
     PGYSSENKSF NPDVHRAHIF GQHVADYMRT LEEEDEEGFK RQFSRYIKLG IRADDLEEIY
     KKAHQAIRAD PTHKKIQKTG VTKKRWNAKK LTNEQRKAKL AEHKTAFLAK IKSETDV
//
DBGET integrated database retrieval system