ID D3UGA2_HELM1 Unreviewed; 1151 AA.
AC D3UGA2;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 24-JAN-2024, entry version 61.
DE SubName: Full=Putative signaling protein {ECO:0000313|EMBL:CBG39523.1};
GN OrderedLocusNames=HMU02610 {ECO:0000313|EMBL:CBG39523.1};
OS Helicobacter mustelae (strain ATCC 43772 / LMG 18044 / NCTC 12198 / 12198)
OS (Campylobacter mustelae).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=679897 {ECO:0000313|EMBL:CBG39523.1, ECO:0000313|Proteomes:UP000001522};
RN [1] {ECO:0000313|EMBL:CBG39523.1, ECO:0000313|Proteomes:UP000001522}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43772 / LMG 18044 / NCTC 12198 / 12198
RC {ECO:0000313|Proteomes:UP000001522};
RX PubMed=20219135; DOI=10.1186/1471-2164-11-164;
RA O'Toole P.W., Snelling W.J., Canchaya C., Forde B.M., Hardie K.R.,
RA Josenhans C., Graham R.L.J., McMullan G., Parkhill J., Belda E.,
RA Bentley S.D.;
RT "Comparative genomics and proteomics of Helicobacter mustelae, an
RT ulcerogenic and carcinogenic gastric pathogen.";
RL BMC Genomics 11:164-164(2010).
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DR EMBL; FN555004; CBG39523.1; -; Genomic_DNA.
DR RefSeq; WP_013022618.1; NC_013949.1.
DR AlphaFoldDB; D3UGA2; -.
DR STRING; 679897.HMU02610; -.
DR KEGG; hms:HMU02610; -.
DR eggNOG; COG3287; Bacteria.
DR eggNOG; COG3437; Bacteria.
DR HOGENOM; CLU_276451_0_0_7; -.
DR Proteomes; UP000001522; Chromosome.
DR CDD; cd00077; HDc; 1.
DR CDD; cd00130; PAS; 3.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.450.20; PAS domain; 4.
DR InterPro; IPR019494; FIST_C.
DR InterPro; IPR013702; FIST_domain_N.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR45228:SF1; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186; 1.
DR PANTHER; PTHR45228; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186-RELATED; 1.
DR Pfam; PF08495; FIST; 1.
DR Pfam; PF10442; FIST_C; 1.
DR Pfam; PF13487; HD_5; 1.
DR Pfam; PF13426; PAS_9; 4.
DR SMART; SM00897; FIST; 1.
DR SMART; SM01204; FIST_C; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00086; PAC; 4.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS51832; HD_GYP; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001522}.
FT DOMAIN 546..622
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 769..845
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 897..1094
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
SQ SEQUENCE 1151 AA; 132022 MW; E9A6C52AF8057B7A CRC64;
MRVCNIIFKD FDQLRRELIA HNVQKVSKEQ FFVQIFMGVA DKNIAKELLD FFDTALDCRV
LLVQSGRETI VSGNIFSSQI LISISCFSHS TLKRAYYPAD RDIDEIARDI RENLASEKTK
LLVVFIACGS FYHQDLLGAI KKELPSLLLC GGRSHPYDMG TMQGLIGDND GIYDHGMICL
SIDSEILSVQ SDFVFGWEDI GLPLKITKSQ HNIVYEINHK KAIEVFEHYL GKTALENLHA
TTYIFPLIYR VNGVPIARVA MKICQDGSVV FNDNIPEGTE VKFGFGLMEN ISRNTELAYA
KIPKNVEGIY MYSCIGHLMF SGKEGMESIL KIFRDEPALC GFFTFGEIYS CRDQNVFLGL
TNTFYCLCEG DFEESQKPSL QKARANLDKG TLVMSTLANL MHRVNQEVME VTKNFETYYE
FVDELMFHII ADAELNILYS NKRISQVSLY DFSQVQGKNC LEFVDAQTRE EITHRILPIL
AEKGQWSGKI YQYRKDGTPY YVKMIIKAIK DREGNVMRYI IGQMDDTADE LKRMALESES
IFLKRSDEER RYLLDQYQSI LDKNQSFFRL DLNRNFIYGN EIFLKITGLK LEEILGKNIY
DFIPVNEQRQ FDKISKDLVE KGYYEGVLEY TRKDGKKVYI QSAAYFIKDL NDIPFEIIAV
GVEITQIIEG VKEIESIQKD VIYSMGAICE GKSRETGNHI IRVAEKGQWS GKIYQYRKDG
TPYYVKMIIK AIKDREGNVM RYIIGQMDDT ADELKRMALE SESIFLKRSD EERRYLLDQY
QSILDKNQSF FRLDLNRNFI YGNEIFLKIT GLKLEEILGK NIYDFIPVNE QRQFDKISKD
LVEKGYYEGV LEYTRKDGKK VYIQSAAYFI KDLNDIPFEI IAVGVEITQI IEGVKEIESI
QKDVIYSMGA ICEGKSRETG NHIIRVAEYS ALLAELCGCS KEDQELLRIA SPMHDIGKVG
ISDAILNKSG KLTPEEFEIM KTHTTIGEEI FKNSNRLILR AAGEIAGSHH EWWNGEGYPR
GIQGEEIPLF GRITALADVF DALSNDRCYK KAWPLPKVLE YVKSLRGKQF QPELLDLFLE
NLDRFLEIGK KYQDKNSSSL FAQKEESCGG GGTKHSSRSN HRLSNSAIKN QLQPLCGMVS
ISDWQRISVE E
//
